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Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1982 Jun;19(3):224–227. doi: 10.1136/jmg.19.3.224

A complex chromosome rearrangement resulting in trisomy 15q22→qter

Patricia N Howard-Peebles *, Paula R Scarbrough *, Joe Sharpe *, Wayne H Finley *, Sara C Finley *
PMCID: PMC1048872  PMID: 7108919

Abstract

A black infant with malformations was found to have trisomy 15q22→qter. The mother had a complex chromosomal rearrangement involving three chromosomes (5, 13, and 15). A comparison with previously published cases of trisomy for distal 15q suggests a pattern of clinical findings including retardation in growth and development, microcephaly, asymmetrical facies, prominent occiput, antimongoloid slant of the palpebral fissures, micrognathia, prominent nose, and congenital heart disease.

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Selected References

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