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. 1982 Aug;19(4):262–265. doi: 10.1136/jmg.19.4.262

Measurement of erythrocyte membrane elasticity as a diagnostic aid in Duchenne muscular dystrophy.

G B Nash, S J Wyard
PMCID: PMC1048890  PMID: 7120313

Abstract

Using a micropipette aspiration technique, erythrocyte membrane shear elastic modulus was determined for 23 patients with Duchenne muscular dystrophy, for 14 female carriers, and for three control groups (age matched boys and adult males and females). On average the elastic modulus was slightly greater than normal for both affected males and female carriers. However, there was overlap in the values from all groups. The decreased deformability of dystrophic membranes demonstrated by the test is not great enough to be used for carrier detection nor to make the possibility of prenatal diagnosis likely.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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