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[Preprint]. 2023 Aug 30:2023.08.29.555158. [Version 1] doi: 10.1101/2023.08.29.555158

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Extended Data Figure 4: — (a) Comparing the movement of the VFTs in the Quis-bound Intermediate 1a (light pink, magenta) and the Quis-bound Intermediate 2a states (cyan and teal) show large rearrangements in the lower lobe, with relatively smaller changes in the upper lobe. Arrows represent the movement of every 5 Cα atoms from the Intermediate 1a state to the Intermediate 2a state.

(b) Single protomer alignment of Quis-bound Intermediate 2a (cyan) and Quis-bound Intermediate 1a (light pink) structures show no change in the Quis binding pocket.