Abstract
We describe a family in which autosomal dominant anterior polar cataracts are segregating in four members over three generations with an apparently balanced reciprocal translocation between chromosomes 2 and 14. We conclude that altered function of a gene or genes on chromosomes 2 or 14 are important in the embryological development of the lens.
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- Morton N. E., Lalouel J. M. Genetic counseling in sex linkage. Birth Defects Orig Artic Ser. 1979;15(5C):9–24. [PubMed] [Google Scholar]
- Mostafa M. S., Temtamy S., El-Gammal M. Y., Sayed S. I., Abdel-Salam M., El-Baroudy R. Genetic studies of congenital cataract. Metab Pediatr Ophthalmol. 1981;5(3-4):233–242. [PubMed] [Google Scholar]