Table 4. Hospitalizations and Respiratory Health in the First 2 Years.

Outcome	No./total (%)		Risk difference, % (95% CI)a	Relative risk (95% CI)a	P valueb
	Minimally invasive surfactant therapy	Control treatment
Hospitalizations with any illness
≥1	77/194 (39.7)	104/204 (51.0)	−11.2 (−18.2 to −4.3)	0.78 (0.66 to 0.92)	.003
≥3	22/194 (11.3)	39/204 (19.1)	−7.8 (−13.7 to −1.8)	0.59 (0.40 to 0.87)	.008
Hospitalizations with respiratory illness
≥1	49/195 (25.1)	78/204 (38.2)	−13.1 (−19.5 to −6.7)	0.66 (0.54 to 0.81)	<.001
≥3	14/195 (7.2)	23/204 (11.3)	−4.1 (−8.6 to 0.4)	0.63 (0.41 to 0.98)	.04
Parent-reported wheeze or breathing difficulty	73/180 (40.6)	104/194 (53.6)	−13.1 (−20.1 to −6.1)	0.76 (0.63 to 0.90)	.002
Use of any bronchodilator therapy	57/180 (31.7)	83/194 (42.8)	−11.2 (−20.0 to −2.4)	0.74 (0.57 to 0.96)	.03
Parent report of a physician diagnosis of asthma	8/180 (4.4)	23/194 (11.9)	−7.6 (−13.7 to −1.5)	0.37 (0.19 to 0.73)	.004

^a Adjusted for gestational age group.

^b P value for relative risk derived from generalized linear model.