Abstract
The basis for using information against linkage to some loci to support linkage to other loci is discussed and data on cystic fibrosis available up to late July 1985 used as an example.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Botstein D., White R. L., Skolnick M., Davis R. W. Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet. 1980 May;32(3):314–331. [PMC free article] [PubMed] [Google Scholar]
- Cook P. J., Noades J. E., Lomas C. G., Buckton K. E., Robson E. B. Exclusion mapping illustrated by the MNSs blood group. Ann Hum Genet. 1980 Jul;44(Pt 1):61–73. doi: 10.1111/j.1469-1809.1980.tb00946.x. [DOI] [PubMed] [Google Scholar]
- Edwards J. H., Parekh J., Kirton V., Hultén M. A meiotic linkage map of the human male. Cytogenet Cell Genet. 1978;22(1-6):698–701. doi: 10.1159/000131056. [DOI] [PubMed] [Google Scholar]
- Edwards J. H. The analysis of X-linkage. Ann Hum Genet. 1971 Feb;34(3):229–250. doi: 10.1111/j.1469-1809.1971.tb00237.x. [DOI] [PubMed] [Google Scholar]
- Eiberg H., Mohr J., Schmiegelow K., Nielsen L. S., Williamson R. Linkage relationships of paraoxonase (PON) with other markers: indication of PON-cystic fibrosis synteny. Clin Genet. 1985 Oct;28(4):265–271. doi: 10.1111/j.1399-0004.1985.tb00400.x. [DOI] [PubMed] [Google Scholar]
- Goodchild M. C., Edwards J. H., Glenn K. P., Grindey C., Harris R., Mackintosh P., Wentzel J. A search for linkage in cystic fibrosis. J Med Genet. 1976 Dec;13(6):417–419. doi: 10.1136/jmg.13.6.417. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MORTON N. E. Sequential tests for the detection of linkage. Am J Hum Genet. 1955 Sep;7(3):277–318. [PMC free article] [PubMed] [Google Scholar]
- Morton N. E., Lindsten J., Iselius L., Yee S. Data and theory for a revised chiasma map of man. Hum Genet. 1982;62(3):266–270. doi: 10.1007/BF00333534. [DOI] [PubMed] [Google Scholar]
- Thompson E. A. Interpretation of LOD scores with a set of marker loci. Genet Epidemiol. 1984;1(4):357–362. doi: 10.1002/gepi.1370010407. [DOI] [PubMed] [Google Scholar]