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Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1998 Dec;35(12):1040–1042. doi: 10.1136/jmg.35.12.1040

Familial occurrence of congenital incomplete prepyloric mucosal diaphragm.

D B Gahukamble 1
PMCID: PMC1051520  PMID: 9863605

Abstract

Incomplete prepyloric mucosal diaphragm (IPMD) is an uncommon congenital anomaly that leads to gastric outlet obstruction in infancy and childhood. This report describes the occurrence of IPMD in six children in a closely knit tribal family from a geographically isolated desert town with a small population in the Sahara. Their records showed similarities of clinical, radiological, operative, and histopathological features. These features, as well as its occurrence in brothers, sisters, and cousins, suggest that this unusual anomaly is transmitted as an autosomal recessive trait.

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Selected References

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  1. Bell M. J., Ternberg J. L., Keating J. P., Moedjona S., McAlister W., Shackelford G. D. Prepyloric gastric antral web: a puzzling epidemic. J Pediatr Surg. 1978 Jun;13(3):307–313. doi: 10.1016/s0022-3468(78)80405-9. [DOI] [PubMed] [Google Scholar]
  2. Bell M. J., Ternberg J. L., McAlister W., Keating J. P., Tedesco F. J. Antral diaphragm--a cause of gastric outlet obstruction in infants and children. J Pediatr. 1977 Feb;90(2):196–202. doi: 10.1016/s0022-3476(77)80629-x. [DOI] [PubMed] [Google Scholar]
  3. Boyden E. A., Cope J. G., Bill A. H., Jr Anatomy and embryology of congenital intrinsic obstruction of the duodenum. Am J Surg. 1967 Aug;114(2):190–202. doi: 10.1016/0002-9610(67)90372-8. [DOI] [PubMed] [Google Scholar]
  4. Keramidas D. C. Letter: Congenital pyloric atresia in siblings. Arch Surg. 1974 Jan;108(1):123–123. doi: 10.1001/archsurg.1974.01350250109031. [DOI] [PubMed] [Google Scholar]
  5. Levenson S. D., Austin R. K., Dietler M. D., Kasarda D. D., Kagnoff M. F. Specificity of antigliadin antibody in celiac disease. Gastroenterology. 1985 Jul;89(1):1–5. doi: 10.1016/0016-5085(85)90737-1. [DOI] [PubMed] [Google Scholar]
  6. Moore C. C. Congenital gastric outlet obstruction. J Pediatr Surg. 1989 Dec;24(12):1241–1246. doi: 10.1016/s0022-3468(89)80559-7. [DOI] [PubMed] [Google Scholar]
  7. Tunell W. P., Smith E. I. Antral web in infancy. J Pediatr Surg. 1980 Apr;15(2):152–155. doi: 10.1016/s0022-3468(80)80006-6. [DOI] [PubMed] [Google Scholar]

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