Abstract
Site-specific cancer mortality data for 20 United States cities have been abstracted from United States Government publications to explore further the hypothesis that fluoridation of water supplies causes cancer. Changes in mortality (standardised for age, sex, and ethnic group) between 1958-62 and 1968-72 in 10 fluoridated and 10 non-fluoridated United States cities have been examined. Of the seven sites (or groups of sites) examined, for only one is there a statistically significant difference between the fluoridated and non-fluoridated cities with respect to average change in mortality. This difference, for cancers of the genital organs, favours the fluoridated cities. These data do not provide evidence of a positive association between fluoridation of water supplies and cancer of any of the sites considered.
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Selected References
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- Armenian H. K., Lilienfeld A. M. The distribution of incubation periods of neoplastic diseases. Am J Epidemiol. 1974 Feb;99(2):92–100. doi: 10.1093/oxfordjournals.aje.a121599. [DOI] [PubMed] [Google Scholar]
- Beral V., Colwell L. Randomised trial of high doses of stilboestrol and ethisterone in pregnancy: long-term follow-up of mothers. Br Med J. 1980 Oct 25;281(6248):1098–1101. doi: 10.1136/bmj.281.6248.1098. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cook-Mozaffari P., Bulusu L., Doll R. Fluoridation of water supplies and cancer mortality. I: A search for an effect in the UK on risk of death from cancer. J Epidemiol Community Health. 1981 Dec;35(4):227–232. doi: 10.1136/jech.35.4.227. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Erickson J. D. Mortality in selected cities with fluoridated and non-fluoridated water supplies. N Engl J Med. 1978 May 18;298(20):1112–1116. doi: 10.1056/NEJM197805182982003. [DOI] [PubMed] [Google Scholar]
- HEASMAN M. A., MARTIN A. E. Mortality in areas containing natural fluoride in their water supplies. Mon Bull Minist Health Public Health Lab Serv. 1962 Aug;21:150–160. [PubMed] [Google Scholar]
- Hoover R. N., McKay F. W., Fraumeni J. F., Jr Fluoridated drinking water and the occurrence of cancer. J Natl Cancer Inst. 1976 Oct;57(4):757–768. doi: 10.1093/jnci/57.4.757. [DOI] [PubMed] [Google Scholar]
- Kinlen L. Cancer incidence in relation to fluoride level in water supplies. Community Health (Bristol) 1974 Sep-Oct;6(2):69–74. [PubMed] [Google Scholar]
- Kinlen L., Doll R. Fluoridation of water supplies and cancer mortality. III: A re-examination of mortality in cities in the USA. J Epidemiol Community Health. 1981 Dec;35(4):239–244. doi: 10.1136/jech.35.4.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wanebo C. K., Johnson K. G., Sato K., Thorslund T. W. Breast cancer after exposure to the atomic bombings of Hiroshima and Nagasaki. N Engl J Med. 1968 Sep 26;279(13):667–671. doi: 10.1056/NEJM196809262791301. [DOI] [PubMed] [Google Scholar]