Abstract
At the end of a multifactorial cardiovascular preventive trial serum thiocyanate was measured in random samples of 1035 cases and 1087 controls. A cut-off point 0.45 mg/dl (77.6/mumol/l) gave a sensitivity of 82.1% among the cigarette smokers in the control group and a specificity of 91.0% among the non-smokers. When the intervention and control groups are compared in terms of self-reported smoking behaviour non-significant differences in mean thiocyanate concentration are observed for those who never smoked, ex-cigarette smokers, actual cigarette smokers, and in four different cigarette smoking categories. Our results fail to confirm the reported pessimistic views concerning the validity of self-reported smoking behaviour in subjects taking part in intervention trials.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Borgers D., Junge B. Thiocyanate as an indicator of tobacco smoking. Prev Med. 1979 May;8(3):351–357. doi: 10.1016/0091-7435(79)90012-4. [DOI] [PubMed] [Google Scholar]
- Butts W. C., Kueheman M., Widdowson G. M. Automated method for determining serum thiocyanate, to distinguish smokers from nonsmokers. Clin Chem. 1974 Oct;20(10):1344–1348. [PubMed] [Google Scholar]
- Cohen J. D., Bartsch G. E. A comparison between carboxyhemoglobin and serum thiocyanate determinations as indicators of cigarette smoking. Am J Public Health. 1980 Mar;70(3):284–286. doi: 10.2105/ajph.70.3.284. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Densen P. M., Davidow B., Bass H. E., Jones E. W. A chemical test for smoking exposure. Arch Environ Health. 1967 Jun;14(6):865–874. doi: 10.1080/00039896.1967.10664853. [DOI] [PubMed] [Google Scholar]
- Gritz E. R., Baer-Weiss V., Jarvik M. E. Titration of nicotine intake with full-length and half-length cigarettes. Clin Pharmacol Ther. 1976 Nov;20(5):552–556. doi: 10.1002/cpt1976205552. [DOI] [PubMed] [Google Scholar]
- Kirk C. J., Lund V. J., Woolcock N. E., Greenhalgh R. M. The effect of advice to stop smoking on arterial disease patients, assessed by serum thiocyanate levels. J Cardiovasc Surg (Torino) 1980 Sep-Oct;21(5):568–569. [PubMed] [Google Scholar]
- Kornitzer M., De Backer G., Dramaix M., Thilly C. The Belgian heart disease prevention project. Modification of the coronary risk profile in an industrial population. Circulation. 1980 Jan;61(1):18–25. doi: 10.1161/01.cir.61.1.18. [DOI] [PubMed] [Google Scholar]
- Kornitzer M., Dramaix M., Kittel F., De Backer G. The Belgian heart disease prevention project: changes in smoking habits after two years of intervention. Prev Med. 1980 Jul;9(4):496–503. doi: 10.1016/0091-7435(80)90044-4. [DOI] [PubMed] [Google Scholar]
- Neaton J. D., Broste S., Cohen L., Fishman E. L., Kjelsberg M. O., Schoenberger J. The multiple risk factor intervention trial (MRFIT). VII. A comparison of risk factor changes between the two study groups. Prev Med. 1981 Jul;10(4):519–543. doi: 10.1016/0091-7435(81)90063-3. [DOI] [PubMed] [Google Scholar]
- Sillett R. W., Wilson M. B., Malcolm R. E., Ball K. P. Deception among smokers. Br Med J. 1978 Oct 28;2(6146):1185–1186. doi: 10.1136/bmj.2.6146.1185. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vogt T. M., Selvin S., Widdowson G., Hulley S. B. Expired air carbon monoxide and serum thiocyanate as objective measures of cigarette exposure. Am J Public Health. 1977 Jun;67(6):545–549. doi: 10.2105/ajph.67.6.545. [DOI] [PMC free article] [PubMed] [Google Scholar]