Abstract
Cancer registration data for a defined geographical area, covering a seven year period, were modified to include the variable "Asian ethnic origin." The data were then used to test the hypothesis that a difference would be found between Asians and non-Asians in the pattern of cancer by site. Whereas the incidence of cancer of all sites appeared to be significantly lower in Asians (p less than 0.05), after taking account of this, and adjusting for the very different age distributions of the two populations, a highly significant difference (p less than 0.0005) was found between the two groups in the distribution of cancer between sites. Although, given the size and young age structure of the Asian population, absolute numbers of cases were small, a significant excess of Asian cases (compared with the expected) occurred for cancer of the tongue, oral cavity, pharynx, and oesophagus. For most sites there were fewer Asian cases than would be expected, particularly so for the stomach, testis, and skin. The results indicate the need for formal epidemiological study to test specific aetiological hypotheses which may account for these apparent differences.
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- Burton-Bradley B. G. Is "betel chewing" carcinogenic? Lancet. 1979 Oct 27;2(8148):903–903. doi: 10.1016/s0140-6736(79)92716-8. [DOI] [PubMed] [Google Scholar]
- Doll R., Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst. 1981 Jun;66(6):1191–1308. [PubMed] [Google Scholar]
- Ramanathan K. Oral carcinoma in the first three decades of life. Med J Malaya. 1972 Sep;27(1):20–26. [PubMed] [Google Scholar]
- Rothman K., Keller A. The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx. J Chronic Dis. 1972 Dec;25(12):711–716. doi: 10.1016/0021-9681(72)90006-9. [DOI] [PubMed] [Google Scholar]
- Schonland M., Bradshaw E. Upper alimentary tract cancer in Natal Indians with special reference to the betel-chewing habit. Br J Cancer. 1969 Dec;23(4):670–682. doi: 10.1038/bjc.1969.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stephen S. J., Uragoda C. G. Some observations of oesophageal carcinoma in Ceylon, including its relationship to betel chewing. Br J Cancer. 1970 Mar;24(1):11–15. doi: 10.1038/bjc.1970.2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WYNDER E. L., BROSS I. J., FELDMAN R. M. A study of the etiological factors in cancer of the mouth. Cancer. 1957 Nov-Dec;10(6):1300–1323. doi: 10.1002/1097-0142(195711/12)10:6<1300::aid-cncr2820100628>3.0.co;2-2. [DOI] [PubMed] [Google Scholar]
- Wahi P. N., Mital V. P., Lahiri B., Luthra U. K., Seth R. K., Arora G. D. Epidemiological study of precancerous lesions of the oral cavity: a preliminary report. Indian J Med Res. 1970 Oct;58(10):1361–1391. [PubMed] [Google Scholar]
- Wynder E. L., Stellman S. D. Comparative epidemiology of tobacco-related cancers. Cancer Res. 1977 Dec;37(12):4608–4622. [PubMed] [Google Scholar]