Skip to main content
Journal of Epidemiology and Community Health logoLink to Journal of Epidemiology and Community Health
. 1984 Sep;38(3):236–239. doi: 10.1136/jech.38.3.236

Seroepidemiology of rubella in Saudi Arabia: an adapted vaccination policy.

M A Abdullah, G Jamjoom, Z A Karrar, A Badreldine, N Al Jishi, S A Taha
PMCID: PMC1052359  PMID: 6470602

Abstract

Rubella haemagglutination antibodies were tested for in sera of 1793 unvaccinated subjects with age ranging from birth to 40 years. This was to assess the immune status of the population and to see the feasibility of introduction and the proper age for rubella vaccination in a Saudi community. Those with titres of greater than or equal to 1:8 were considered as seropositive. The lowest level of antibodies was seen among the 10-18 month age group. All children aged 2-5 years were seropositive as were 75% of the elementary school girls. Only 90-95% of the women of childbearing age were seropositive, however, leaving an immune gap of 5-10%. Unnecessary mass vaccination of young children is discouraged. Rubella vaccine should be given to all final elementary school girls and all women of childbearing age after screening, whenever possible. Special catchment zones are suggested for the latter group. Further nationwide seroepidemiological surveys are recommended for the other parts of the Saudi Kingdom.

Full text

PDF
236

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Banatvala J. E. Rubella vaccination: remaining problems. Br Med J (Clin Res Ed) 1982 May 1;284(6325):1285–1286. doi: 10.1136/bmj.284.6325.1285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Best J. M., Harcourt G. C., Druce A., Palmer S. J., O'Shea S., Banatvala J. E. Rubella immunity by four different techniques: results of challenge studies. J Med Virol. 1980;5(3):239–247. doi: 10.1002/jmv.1890050308. [DOI] [PubMed] [Google Scholar]
  3. Cockburn W. C. World aspects of the epidemiology of rubella. Am J Dis Child. 1969 Jul;118(1):112–122. doi: 10.1001/archpedi.1969.02100040114019. [DOI] [PubMed] [Google Scholar]
  4. Dudgeon J. A., Marshall W. C., Peckham C. S. Rubella vaccine trials in adults and children. Comparison of three attenuated vaccines. Am J Dis Child. 1969 Aug;118(2):237–243. doi: 10.1001/archpedi.1969.02100040239015. [DOI] [PubMed] [Google Scholar]
  5. Dudgeon J. A. Measles and rubella vaccines. Arch Dis Child. 1977 Dec;52(12):907–911. doi: 10.1136/adc.52.12.907. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Guidelines for community menopausal clinics. Br Med J (Clin Res Ed) 1983 Jul 23;287(6387):286–287. doi: 10.1136/bmj.287.6387.286-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hathout H., Al-Nakib W., Lilley H., Abo-Ahmed H. S., Nosseir A. F. Seroepidemiology of rubella in Kuwait: an alternative vaccination policy. Int J Epidemiol. 1978 Mar;7(1):49–53. doi: 10.1093/ije/7.1.49. [DOI] [PubMed] [Google Scholar]
  8. Inouye S. Micro-modification of kaolin treatment of serum for the rubella haemagglutination-inhibition test. J Med Microbiol. 1976 Nov;9(4):501–502. doi: 10.1099/00222615-9-4-501. [DOI] [PubMed] [Google Scholar]
  9. Khalifa A. S., Abdel-Wahab K. S., Imam I. Z. Seroimmunity to rubella among an Egyptian population. J Infect Dis. 1973 May;127(5):567–570. doi: 10.1093/infdis/127.5.567. [DOI] [PubMed] [Google Scholar]
  10. Krugman S. Rubella immunization: progress, problems and potential solutions. Am J Public Health. 1979 Mar;69(3):217–219. doi: 10.2105/ajph.69.3.217. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Lawless M. R., Abramson J. S., Harlan J. E., Kelsey D. S. Rubella susceptibility in sixth graders: effectiveness of current immunization practice. Pediatrics. 1980 Jun;65(6):1086–1089. [PubMed] [Google Scholar]
  12. Modlin J. F., Herrmann K., Brandling-Bennett A. D., Eddins D. L., Hayden G. F. Risk of congenital abnormality after inadvertent rubella vaccination of pregnant women. N Engl J Med. 1976 Apr 29;294(18):972–974. doi: 10.1056/NEJM197604292941802. [DOI] [PubMed] [Google Scholar]
  13. Mortimer P. P., Edwards J. M., Porter A. D., Tedder R. S., Mace J. E., Hutchinson A. Are many women immunized against rubella unnecessarily? J Hyg (Lond) 1981 Aug;87(1):131–138. doi: 10.1017/s0022172400069308. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Rawls W. E., Melnick J. L., Bradstreet C. M., Bailey M., Ferris A. A., Lehmann N. I., Nagler F. P., Furesz J., Kono R., Ohtawara M. WHO collaborative study on the sero-epidemiology of rubella. Bull World Health Organ. 1967;37(1):79–88. [PMC free article] [PubMed] [Google Scholar]
  15. Vaile M. S. Factors influencing rubella immunity in women. Br Med J (Clin Res Ed) 1981 Feb 28;282(6265):738–738. doi: 10.1136/bmj.282.6265.738-a. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Epidemiology and Community Health are provided here courtesy of BMJ Publishing Group

RESOURCES