Table 1.
Drosophila melanogaster strains.
| Genotype in the Text | Genotype 1 | Characteristic |
|---|---|---|
| Oregon R | + | Wild-type strain competent in all DNA damage response mechanisms. |
| ATMtefu | w; tefu e6 [be] | Mutant deficient in the protein kinase tefu (telomere fusion), homologue of ATM in mammals. |
| ATRmei−29D | w; mei-4129D/y{UASp41} mei-4129D; p{mtα}/+ | Mutant deficient in the protein kinase mei-41 (meiotic-41), ortholog of ATR in mammals. |
| Chk1grp/Chk2lok | w/+; grp209 lok30/grpZ5170 lok30 | Mutant deficient in the protein kinases: grp (grappes) and lok (localized ovarian kinase), respectively orthologs of Chk1 and Chk2 in mammals. |
| Chk1grp | w/+; grp209/grpZ5170 | Mutant deficient in the protein kinase grp (grapes), ortholog of Chk1 in mammals. |
| p53dp53 | y1 w1118; p535A−1−4 | Mutant deficient in the dp53 protein (tumor suppressor), ortholog of p53 in mammals. |
1 All the strains were kept at 25 ± 2 °C, in vial with standard culture medium based on yeast, agar, sucrose and flour.