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. 2023 Sep 12;28(18):6585. doi: 10.3390/molecules28186585

Table 3.

ANOVA for the response surface quadratic model.

Source SS DF MS F Pr > F Sig
Model 16.45 14 1.18 30.7 <0.0001 significant
A 0.3468 1 0.3468 9.06 0.0094 **
B 0.472 1 0.472 12.33 0.0035 **
C 0.1261 1 0.1261 3.29 0.091
D 8.38 1 8.38 219.07 <0.0001 ***
AB 0.5929 1 0.5929 15.49 0.0015 **
AC 0.0009 1 0.0009 0.0235 0.8803
AD 0.3721 1 0.3721 9.72 0.0076 **
BC 0.009 1 0.009 0.2358 0.6347
BD 1.48 1 1.48 38.58 <0.0001 ***
CD 0.4225 1 0.4225 11.04 0.005 **
A2 3.63 1 3.63 94.79 <0.0001 ***
B2 0.1515 1 0.1515 3.96 0.0665
C2 0.121 1 0.121 3.16 0.0971
D2 1.25 1 1.25 32.68 <0.0001 ***
Residual 0.5358 14 0.0383
Lack of Fit 0.4336 10 0.0434 1.7 0.3216 not significant
Pure Error 0.1021 4 0.0255
Cor Total 16.99 28

Note: SS: Sum of squares; DF: Degree of freedom; MS: Mean square; Pr: Probability; ** p < 0.01, *** p < 0.001; R2 = 0.8203, Adjusted R2 = 0.9369, Predicted R2 = 0.8436, C.V.% = 2.076.