Skip to main content
The British Journal of Venereal Diseases logoLink to The British Journal of Venereal Diseases
. 1952 Jun;28(2):50–60. doi: 10.1136/sti.28.2.50

Pathogenesis of the Jarisch-Herxheimer Reaction

A REVIEW OF CLINICAL AND EXPERIMENTAL OBSERVATIONS*

Albert Heyman 1,2,3, Walter H Sheldon 1,2,3, Lilian D Evans 1,2,3
PMCID: PMC1053806  PMID: 14935211

Full text

PDF
50

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. COALE L. H., ALLEN M. S., DELP M. H. Penicillin treatment of cardiovascular syphilis. J Kans Med Soc. 1950 Mar;51(3):102–109. [PubMed] [Google Scholar]
  2. DERBES V. J., DENT J. H., WEAVER N. K., VAUGHAN D. D. Response of tuberculin skin test to ACTH and cortisone in tuberculous guinea pigs. Proc Soc Exp Biol Med. 1950 Nov;75(2):423–426. doi: 10.3181/00379727-75-18218. [DOI] [PubMed] [Google Scholar]
  3. GOLD H. Aureomycin in the treatment of anthrax. Am J Med. 1950 Jan;8(1):31–33. doi: 10.1016/0002-9343(50)90339-1. [DOI] [PubMed] [Google Scholar]
  4. HEYMAN A., PATTERSON J. L., Jr, NICHOLS F. T., Jr, JONES R. W. Cerebral blood flow and metabolism in neurosyphilis; the effects of penicillin, induced fever, and other therapeutic measures. Am J Syph Gonorrhea Vener Dis. 1951 Jul;35(4):301–311. [PubMed] [Google Scholar]
  5. LONG J. B., FAVOUR C. B. The ability of ACTH and cortisone to alter delayed type bacterial hypersensitivity. Bull Johns Hopkins Hosp. 1950 Sep;87(3):186–202. [PubMed] [Google Scholar]
  6. SHAFFER B., SHENKIN H. A. Fatal Herxheimer reaction following penicillin therapy; report of a case of syphilitic pachyleptomeningitis. Am J Syph Gonorrhea Vener Dis. 1950 Jan;34(1):78–82. [PubMed] [Google Scholar]
  7. SHELDON W. H., CUMMINGS M. M., EVANS L. D. Failure of ACTH or cortisone to suppress tuberculin skin reaction in tuberculous guinea pigs. Proc Soc Exp Biol Med. 1950 Nov;75(2):616–618. doi: 10.3181/00379727-75-18283. [DOI] [PubMed] [Google Scholar]
  8. SHELDON W. H., HEYMAN A., EVANS L. D. The production of Herxheimer reactions by injection of immune serum in rabbits with experimental syphilis. Am J Syph Gonorrhea Vener Dis. 1951 Sep;35(5):405–410. [PubMed] [Google Scholar]
  9. SINCLAIRE H. A., WEBSTER B. The problem of the Jarisch-Herxheimer reaction in the penicillin therapy of cardiovascular syphilis. Am J Syph Gonorrhea Vener Dis. 1951 Jul;35(4):312–318. [PubMed] [Google Scholar]
  10. SUCHETT-KAYE A. I. Penicillin in Weil's disease. Lancet. 1951 Jan 13;1(6646):90–92. doi: 10.1016/s0140-6736(51)91171-3. [DOI] [PubMed] [Google Scholar]
  11. WHEELER C. E., CURTIS A. C. Treatment of cardiovascular syphilis with penicillin. Am J Syph Gonorrhea Vener Dis. 1951 Jul;35(4):319–328. [PubMed] [Google Scholar]
  12. WHORTON C. M., DENHAM S. W. The occurrence of the Jarisch-Herxheimer reaction in a patient with gummatous syphilitic aortitis. Am J Syph Gonorrhea Vener Dis. 1951 May;35(3):255–262. [PubMed] [Google Scholar]

Articles from British Journal of Venereal Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES