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. 1987 Sep;85(1):30–33. doi: 10.1104/pp.85.1.30

Inhibition of Na+/H+ Antiport Activity in Sugar Beet Tonoplast by Analogs of Amiloride 1

Eduardo Blumwald 1,2,3, Edward J Cragoe Jr 1,2,3, Ronald J Poole 1,2,3
PMCID: PMC1054197  PMID: 16665675

Abstract

The effects of amiloride and a series of amiloride analogs have been tested on the Na+/H+ antiport activity in intact vacuoles and tonoplast vesicles isolated from sugar beet cell suspension cultures. There is a competitive interaction between amiloride analogs and sodium. Substitution of one or both H-atoms of the 5-amino group of amiloride (apparent Ki about 150 micromolar) resulted in a 3- to 200-fold increase in inhibitory potency of the antiport activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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