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Revista da Sociedade Brasileira de Medicina Tropical logoLink to Revista da Sociedade Brasileira de Medicina Tropical
. 2023 Sep 22;56:e0073-2023. doi: 10.1590/0037-8682-0073-2023

Enterobius vermicularis in Brazil: An integrative review

Maria Fantinatti 1,2, Alda Maria Da-Cruz 2,3
PMCID: PMC10550099  PMID: 37792827

ABSTRACT

Enterobius vermicularis, an intestinal helminth, is transmitted through the ingestion of eggs found in food, water, dust, or other fomites, including infected individuals. This review aimed to examine the frequency and distribution of E. vermicularis infections in Brazil between 1991 and 2022. The conducted bibliographic survey revealed that the frequency of E. vermicularis infections in Brazil ranged from 0.1 to 26.1%, depending on factors such as population ethnicity, individual age group, geographic area, time frame, and diagnostic method. However, these findings were based on a limited number of publications, suggesting that the actual prevalence rates of E. vermicularis infection may still be unknown and potentially underestimated.

Keywords: Enterobius vermicularis, Prevalence, Frequency, Brazil

INTRODUCTION

Enterobiasis, also known as enterobiosis, is a globally distributed parasitic disease, not confined solely to underdeveloped countries. It is estimated that over 40 million people in the USA are infected with Enterobius vermicularis, commonly known as pinworm1 1 , 2 . Notably, a frequent correlation has been reported between enterobiasis and families of lower socioeconomic status 3 .

In Brazil, the proliferation of slums, coupled with the high occupancy rate per dwelling, fosters the spread of parasites, including pinworms. Similarly, settings like day care centers and schools may heighten the risk of disease transmission 3 .

This review aimed to examine the distribution and frequency of E. vermicularis infection cases in Brazil from 1991 to 2022.

METHODOLOGY

An exploratory and descriptive bibliographic review was conducted between January and June 2023, focusing on the prevalence of E. vermicularis in Brazil. The research utilized the Medical Literature Analysis and Retrieval System Online (Medline) electronic database and Virtual Health Library (VHL) Regional Portal.

The search for the etiological agent, “Enterobius,” was delimited using Medical Subject Headings (MeSH) terms. Additionally, the species’ synonym, “pinworm,” and the geographical area, “Brazil,” were included in the search parameters. The Boolean operators “OR” and “AND” were utilized to combine these descriptors. Consequently, the following search strategy was formulated: 1) ((Enterobius) OR (pinworm)) AND (Brazil).

The inclusion criterion for manuscript selection was the full retrieval of articles. Studies were excluded if they were unavailable, utilized archaeological material, did not involve human samples, used samples known to be positive for enteroparasites, did not focus on the Enterobius worm, or were bibliographic reviews. In cases of duplicate studies across search platforms, only one was included.

RESULTS

Annual number of publications addressing the positivity of Enterobius vermicularis in Brazil.

A bibliographic survey of the Medline and VHL electronic libraries yielded 68 and 81 papers, respectively. Following the application of inclusion and exclusion criteria, 56 studies conducted on human samples within the Brazilian territory were selected from Medline and VHL for inclusion in this review (Table 1).

TABLE 1: Positivity of Enterobius vermicularis in Brazil up to 2022, according year in wich the samples were obtained, city and state, population studied, age, number of individuals or samples, diagnostic technique, prevalence and reference.

Year in which the samples were obtained City/State Population studied Age Number of individuals or samples Diagnostic technique Positivity Reference
1984 Guaporé, Laje e Ribeirão, Pacaas-Novos/RO Indigenous All 639 Spontaneous sedimentation 2% Santos et al. 1985
1984 Guarulhos/SP Schoolers 6-16 years 913 Spontaneous sedimentation 1.9% (6-10 years = 2.6% Chieffi et al. 1988
11-16 years = 1%)
1987 Parque Xingu/MT Indigenous All 69 Flotation in Sodium Chloride 26.1% Ferreira et al. 1991
Spontaneous sedimentation
1986-1990 Campinas/SP Health center users All 770 NR 1.4% (1-7 years = 6%) Gioia 1992
(8-18 years = 0,9%)
(over 19 years = 0%)
1992 Campinas/SP Farm dwellers All 82 Centrifuge-sedimentation in formaldehyde-ether 1.4% (under 16 years old = 3.7%) Kobayashi et al. 1995
(over 16 years old = 0 %)
1989-1990 Uberlândia/MG Food handlers 20-66 years 264 Spontaneous sedimentation 1% De Rezende et al. 1997
1994 Uberlândia/MG Children 4 months-7 years 300 Spontaneous sedimentation 4% Machado et al. 1998
NR Sorocaba/SP Preschoolers Up to 5 years 1.050 Spontaneous sedimentation 1.2% Coelho et al. 1999
1992-1996 São José da Bela Vista/SP Public hospital users 0-68 years 1.032 Spontaneous sedimentation 2.2% Tavares-Dias and Grandini 1999
NR Niterói/RJ Preschoolers and daycare workers 1-6 years 340 (children) Spontaneous sedimentation 0.8% (children) Uchôa et al. 2001
Over 18 years 54 (staff) Flotation in Zinc Sulfate 0% (staff)
NR Campinas/SP Schoolers 6-11 years 146 Spontaneous sedimentation 5% Iñiguez et al. 2002
Flotation in Sodium Chloride
Flotation in Zinc Sulfate
Centrifuge-sedimentation in formaldehyde-ether
NR Cascavel/CE General population All 251 Spontaneous sedimentation 2.4% Heukelbach et al. 2004
2001 Presidente Prudente/SP NR 1-12 years 1.000 Spontaneous sedimentation 1.9% Tashima and Simões 2004
Flotation in Zinc Sulfate
Adhesive tape (when requested)
2001-2002 Doutor Camargo, Rural population All 181 Spontaneous sedimentation 8.8% Guilherme et al. 2004
Ivatuba, Floresta/PR (32- Floresta Flotation in Zinc Sulfate (Floresta = 31.4%
107- Ivatuva Ivatuva = 6.5%
42- Doutor Camargo) Doutor Camargo = 5.2%)
2003-2004 Eirunepé/AM NR 2 months-80 years 413 Spontaneous sedimentation 0.5% Araújo et al 2005
2002 Botucatu/SP Preschoolers 0-6 years 279 Spontaneous sedimentation 10.0% De Carvalho et al. 2006
Flotation in Zinc Sulfate
Centrifuge-sedimentation in formaldehyde-ether
Adhesive tape
2002-2003 Uruguaiana/RS Preschoolers 5 months-6 years 1288 Spontaneous sedimentation 0.8% Chavez et al. 2006
2005-2006 Rio de Janeiro/RJ Pediatric patients with gastroenteritis 0-5 years 213 Centrifuge-sedimentation in formaldehyde-ether 0.5% Carvalho-Costa et al. 2007
1995-2005 Botucatu/SP Patients with appendicitis All 1.600 Histopathological 1.4% Da Silva et al. 2007
2005 Vespasiano/MG Preschoolers 1-5 years 176 Centrifuge-sedimentation in formaldehyde-ether 2.5% Barçante et al. 2008
1969-2004 Caxias do Sul/RS Schoolers 6-14 years 9.789 Spontaneous sedimentation (1969-1970) 8% Basso et al. 2008
Centrifuge-sedimentation in formaldehyde-ether (1971-2004)
Adhesive tape (1980-1982)
1996 Abadia dos Dourados/MG Rural and Urban population All 376 Spontaneous sedimentation 0.5% (Rural population = Machado et al. 2008
1.1% Urban population = 0%)
1996-1997 Uberlândia/MG NR 0-15 years 160 Spontaneous sedimentation 8.8% Machado et al. 2008
2000 São Paulo/SP Children 2-14 years 120 Kato-katz Spontaneous sedimentation 1.7% Korkes et al. 2009
Flotation in Zinc Sulfate
2004 Presidente Bernardes/SP Children 0-6 years 101 Spontaneous sedimentation 8.9% Tashima et al. 2009
Flotation in Zinc Sulfate
2006 Berilo/MG Rural and Urban population 0-90 years 149 Kato-katz 2% Martins et al. 2009
Centrifuge-sedimentation in formaldehyde-ether (Rural population = 1.6%
Urban population = 2.3%)
2007-2008 Coari/AM Preschoolers NR 211 Spontaneous sedimentation 2.4% Monteiro et al. 2009
NR Patos de Minas/MG Children 0-6 years 161 Spontaneous sedimentation 0.6% Silva and Gonçalves da Silva 2010
2007-2008 Chapadinha/MA General population All 3933 Spontaneous sedimentation 1% Silva et al. 2010
2006-2008 Porto Alegre/RS People with special needs 2-60 years 146 Spontaneous sedimentation 3.4% Silva et al. 2010
Flotation in Zinc Sulfate
2007 Manaus/AM General population 0-85 years 400 Spontaneous sedimentation 11% Oliveira et al. 2010
2008 Santa Isabel do Rio Negro/AM NR 0-5 years 113 (Adhesive tape) Adhesive tape 15% (Adhesive tape) Valverde et al. 2011
463 (Centrifuge-sedimentation in formaldehyde-ether) Centrifuge-sedimentation in formaldehyde-ether 0.6% (Centrifuge-sedimentation in formaldehyde-ether)
NR Natal/RN Children residing in orphanage 4-12 years 86 Adhesive tape 72.1% Campos et al. 2011
1996-1997 Uberlândia/MG Preschoolers and daycare workers All 180 Spontaneous sedimentation 2.2% Machado et al. 2010
2011-2013 Parnaíba/PI Food handlers 20-59 years 251 Spontaneous sedimentation 13% Fernandes et al. 2014
Flotation in Sodium Chloride
NR Miranda/MS Indigenous 1-33 years 134 Spontaneous sedimentation 3% Neres-Norberg et al. 2014
Flotation in Sodium Chloride
2010 Pelotas/RS Ostomized individuals All 71 Centrifuge-sedimentation in formaldehyde-ether 2.8% Santos et al. 2014
Flotation in Zinc Sulfate
2012 Florianópolis/SC Preschoolers 2-6 years 57 Spontaneous sedimentation 1.8% Santos et al. 2014
Flotation in Zinc Sulfate
2015 Londrina/PR General population Over 18 years 187 Spontaneous sedimentation 0.5% Benitez et al. 2016
Flotation in Zinc
Sulfate
Flotation in Sodium Chloride
2011-2014 Caxias do Sul/RS Food handlers All 331 NR 0.3% Porto et al. 2016
2010-2011 Ituiutaba/SP Preschoolers and daycare workers 0-10 years 181 (children = 140 Spontaneous sedimentation 2.3% (children) Moura et al. 2017
Over 18 years Staff = 41) Centrifuge-sedimentation in formaldehyde-ether 2.4% (staff)
Flotation in Sodium Chloride
2012-2013 Ribeirão Preto/SP NR 3-12 years 576 TF-Test Kit 7.3% Fonseca et al. 2017
NR São Matheus/ES intellectual and/or multiple deficiency 15-61 years 50 Spontaneous sedimentation 10.7% Oliveira Albuquerque and Andrade de Souza 2017
NR Duque de Caxias/RJ NR 1-85 years 180 Spontaneous sedimentation 13% Valença Barbosa et al. 2017
2015 Santo Antonio de Jesus/BA Rural population All 144 Spontaneous sedimentation 10.4% Andrade et al. 2018
Adhesive tape Kato-katz
2013 Sumidouro/RJ General population 2-87 years 294 Spontaneous sedimentation 0.7% Barbosa et al. 2018
Flotation in Sodium Chloride
2016 Ipê/RS Rural and Urban population 6-11 years 124 Spontaneous sedimentation 20% Zanotto et al. 2018
Flotation in Zinc Sulfate
2008-2009 (Viçosa) Viçosa e Muriaé/MG Rural and Urban population All 419 (Viçosa) Spontaneous sedimentation 0.95% (Viçosa) Iasbik et al. 2018
2007-2015 (Muriaé) 1832 (Muriaé) 0.05% (Muriaé)
2016 João Pessoa/PB Schoolers 5-16 years 150 Spontaneous sedimentation 5.7% Monteiro et al. 2018
Para-test kit
2013 Diamantina/MG Quilombola community All 78 Spontaneous sedimentation 0.0% Eustachio et al. 2019
2018 Bandeirantes/PR Schoolers 10-15 years 112 Spontaneous sedimentation 0.9% Almeida et al. 2020
Flotation in Zinc
Sulfate
Kato-katz
2015 Maceió/AL General population All 1.581 Spontaneous sedimentation 0.4% Araújo et al. 2020
2017-2019 Vitória da Conquista/BA Children and adolescents attending non-governmental organizations 4-17 years 116 Spontaneous sedimentation 2.6% Alves et al. 2021
2016 Foz do Iguaçu/PR Preschoolers 3-5 years 178 Spontaneous sedimentation 1.7% Ferreira et al. 2021
Flotation in Zinc Sulfate
2015-2016 Sinop/MT Preschoolers and Schoolers 3-12 years 646 Spontaneous sedimentation 0.8% Carvalho et al. 2022
Flotation in Zinc
Sulfate
Flotation in Sodium Chloride
2017-2019 Rio Branco/AC General population All 53.199 Spontaneous sedimentation 0.1% Sinhorin et al. 2022
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NR: Not reported.

The research conducted for this review did not specify a time frame concerning the initial published study. The earliest three studies identified originated from the 1960s (two in 1965 and one in 1967); however, owing to their unavailability, they were excluded from this review. Consequently, the first study incorporated into this review dates back to 1985, involving a survey conducted using clinical stool samples from the indigenous population of Pacaas-Novos in the state of Rondônia 4 .

E. vermicularis has been detected in human feces across all regions of Brazil. However, a greater number of studies (28/56) 3 , 5 - 31 originate from the Southeast region. Despite this region boasting the highest human development indices in the country, and thus an anticipated lower frequency of enteroparasite infection, it also houses the majority of research institutes/universities and receives the most science-related investments. This fact may account for our findings.

In 19 out of 27 states, including the Federal District, there were no reported instances of E. vermicularis circulation. This absence of reports could be attributed to inadequate research methods for the parasite, insufficient investment in research, or less plausibly, the absence of helminths in these states.

Diagnostic strategies for Enterobius vermicularis

The available data on the frequency of E. vermicularis was derived from 25 studies that employed more than one technique, each based on different methodological principles 3 , 12 - 14 , 20 - 22 , 25 , 29 , 32 - 47 . Conversely, 29 studies utilized a single technique, either in isolation or in conjunction with helminth larvae concentration techniques 4 , 5 , 7 - 11 , 15 - 19 , 23 , 24 , 26 - 28 , 30 , 31 , 35 , 48 - 56 . Of these, sedimentation methods were the most frequently employed (23/29) 4 , 5 , 8 - 11 , 18 , 19 , 23 , 24 , 27 , 28 , 30 , 31 , 35 , 48 - 52 , 54 - 56 .

This review found that only 6 out of 56 studies utilized adhesive tape for diagnosis 3 , 14 , 34 , 36 , 42 , 53 . The adhesive tape method demonstrated higher sensitivity in diagnosing E. vermicularis infection 42 compared to other methods. In one study, the gummed tape method was employed for a shorter duration than the entire study 34 , while in another, the method was only applied when clinically indicated 14 . Given the biological characteristics of Enterobius, the Graham method could potentially enhance positivity in studies. The Graham method has also been employed for environmental samples, such as public restroom surfaces and transportation means, where Enterobius presence has been reported in Brazil 10 , 57 - 59 .

The methodologies employed in these studies, either individually or in combination, indicate a broad investigation into the presence of protozoa and geohelminths. Occasionally, evolutionary forms of E. vermicularis were observed. This observation underscores the apparent lack of interest in E. vermicularis research. Consequently, most of the existing data on the frequency of E. vermicularis infections are derived from studies with experimental designs that are not adequately suited for research on this particular helminth.

Prevalence of Enterobius vermicularis in Brazil

In Brazil, E. vermicularis notification is not mandatory, and no nationwide study exists to investigate this helminth. Consequently, determining the prevalence of E. vermicularis is challenging owing to the reliance on data from independent, cross-sectional research conducted by various groups with local scope and specific populations. Furthermore, the lack of standardization in diagnostic methodologies complicates this task. The highest frequency of E. vermicularis was found in samples collected in 1987 from the indigenous population of Xingu Park in Mato Grosso, with a prevalence of 26.1%. These samples were analyzed using sedimentation in water and sodium chloride solution floating techniques 32 . Despite employing similar diagnostic methods, other studies conducted in Rondônia and Mato Grosso do Sul on samples from indigenous populations reported a significantly lower frequency of E. vermicularis (2% and 3%, respectively) 4 , 38 .

Only a single study evaluated individuals with special needs, rendering it impossible to ascertain the frequency within this population in the country 60 .

E. vermicularis infection predominantly impacts children 5 , 6 , 7 , 12 , 24 , 56 . Excluding the study conducted in Sumidouro/RJ and Ituiutaba/SP 25 , 29 , the infection frequency among children-only studies ranged from 0.5% in Rio de Janeiro/RJ to 72.1% in Natal/RN. The infection rates among children in Brazil fluctuate based on the region under study and the characteristics of the child population, such as family income, residential area (rural or urban), and primarily, their exposure to crowded environments. The presence of Enterobius in consumable vegetables has also been documented 20 , 61 , suggesting these foods may serve as a transmission route for helminths in Brazil. Among food handlers, the infection frequency varied from 0.3 to 13% depending on the region 8 , 37 , 62 , underscoring the potential role of this population in Enterobius transmission, as highlighted in the study by Fernandes et al. (2014) 37 .

The presence of infective E. vermicularis eggs in public environments, such as bathrooms and buses, is concerning because of the possibility of contamination 10 , 57 - 59 . This potential for contamination elucidates the sporadic instances of E. vermicularis infection.

Anal pruritus was a common complaint (50%) among children attending a daycare center in a Rio de Janeiro/RJ community. This prompted an investigation into the prevalence of E. vermicularis infection within this demographic. In 2015, 5.9% (4/68) of the children, aged 1-4 years, were found to be infected with E. vermicularis, as determined by the Graham method.

Over the past 6 months, drugs were administered to more than 22% of these children to treat worms infection. The reported usage of antiparasitic drugs, in conjunction with the frequency of enteroparasite occurrence and its primary clinical manifestation, prompted us to question the estimated prevalence rates of helminths in Brazil.

The papers reviewed generally indicated that data on E. vermicularis infection frequency are derived from studies primarily designed to survey intestinal parasites. Therefore, the diagnostic methodologies employed exhibited lower sensitivity in detecting parasite eggs. An exception was the study by Campos et al. (2011), which aimed to ascertain pinworm prevalence and its association with enuresis cases in children from an orphanage 53 . The high infection frequency observed in this study (72.1%) resulted from three factors: 1) the age range of the population; 2) overcrowding; and 3) the diagnostic methodology, inclusive of sample collection preparation.

FINAL CONSIDERATIONS

The prevalence of E. vermicularis infections in Brazil between 1991 and 2022 ranged from 0.1-72.1%. This variation was influenced by factors such as population ethnicity, age group, geographic location, time period, and diagnostic methods. However, these statistics were derived from a limited number of publications, suggesting a potential underestimation of the actual prevalence rates of E. vermicularis infection.

E. vermicularis eggs, already infective upon release, can be transmitted directly through person-to-person contact. This makes crowded environments such as day care centers, schools, and nursing homes conducive to the spread of this helminth. Furthermore, in Brazil, favelas are home to over 17 million people, constituting 8% of the population 63 . In these settings, population agglomeration in intra- and peridomiciles is common, thereby promoting (re)infection. In such high-frequency environments, recurrent infections are anticipated. Consequently, the chronicity of E. vermicularis infection may be more prevalent than anticipated, and the issue of parasite resistance to available drugs is a subject of ongoing debate.

In Brazil, many states and municipalities lack reports of E. vermicularis infection, while others present only few reports, indicating that the geographical distribution of this infection requires further investigation. The majority of these studies are typically cross-sectional, stemming from individual research groups, and primarily focus on local parasitological surveys. However, the methodologies employed are often incomparable and may not be the most sensitive for parasite identification. The application of unsuitable techniques can result in false-negative outcomes, potentially extending the parasite-host interaction, which may cause perianal itching and gastrointestinal symptoms. Additionally, the infection has been linked to conditions such as vulvovaginitis and appendicitis.

This review consolidates studies published from 1985 to 2022, showcasing the prevalence of enterobiasis across various Brazilian states and the diagnostic strategies employed. In 13% (7/54) of these studies, an E. vermicularis frequency equal to or exceeding 10% was noted. However, the absence of a national infection survey and a dearth of research targeting parasite identification precludes definitive conclusions about whether the distribution of E. vermicularis is on the rise or decline. The limited understanding of E. vermicularis transmission dynamics hampers the development of strategic control measures targeting potential transmission sources.

ACKNOWLEDGMENTS

None.

Footnotes

Financial Support: This work was supported by CNPq Universal Program (Grant 435015/2018-4), FAPERJ (Grant E-26/202.078/2020), Instituto Oswaldo Cruz/FIOCRUZ-Brazilian Ministério da Saúde (internal funds PAEF IOC-023-FIO-18-53), and Universidade Federal de Roraima. M.F. was supported by a fellowship from FAPERJ Nota 10 (E-26/202.077/2020). A.M.D.-C. has a research fellowship from CNPq and FAPERJ (CNE).

REFERENCES

  • 1.Burkhart CN, Burkhart CG. Assessment of frequency, transmission, and genitourinary complications of enterobiasis (pinworms) Int J Dermatol. 2005;44(10):837–840. doi: 10.1111/j.1365-4632.2004.02332.x. [DOI] [PubMed] [Google Scholar]
  • 2.Cook GC. Enterobius vermicularis infection. Gut. 1994;35(9):1159–1162. doi: 10.1136/gut.35.9.1159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.de Carvalho TB, de Carvalho LR, Mascarini LM. Occurrence of enteroparasites in day care centers in Botucatu (São Paulo State, Brazil) with emphasis on Cryptosporidium sp., Giardia duodenalis and Enterobius vermicularis. Rev Inst Med Trop Sao Paulo. 2006;48(5):269–273. doi: 10.1590/s0036-46652006000500006. [DOI] [PubMed] [Google Scholar]
  • 4.Santos RV, Coimbra Jr, Ott AMT. Estudos epidemiológicos entre grupos indígenas de Rondônia III: Parasitoses intestinais nas populações dos vales dos rios Guaporé e Mamoré. Cad Saude Publica. 1985;1:467–477. [Google Scholar]
  • 5.Chieffi PP, Waldman EA, Dias RSDS, Torres DMAGV, Chimara R, Mizumoto LC, et al. Enteroparasitoses no município de Guarulhos, SP. 1. Prevalência de infecção entre escolares residentes no bairro de Taboão, em junho de 1984. Rev Inst Adolfo Lutz. 1988;48:75–85. [Google Scholar]
  • 6.Gioia I. Prevalência de parasitoses intestinais entre os usuários do Centro de Saúde do Distrito de Sousas, Campinas, SP (1986-1990) [The prevalence of intestinal parasitoses among the users of the Health Center of Sousas District, Campinas, São Paulo (1986-1990)] Rev Soc Bras Med Trop. 1992;25(3):177–182. doi: 10.1590/s0037-86821992000300005. [DOI] [PubMed] [Google Scholar]
  • 7.Kobayashi J, Hasegawa H, Forli AA, Nishimura NF, Yamanaka A, Shimabukuro T, et al. Prevalence of intestinal parasitic infection in five farms in Holambra, São Paulo, Brazil. Rev Inst Med Trop São Paulo. 1995;37(1):13–18. doi: 10.1590/s0036-46651995000100003. [DOI] [PubMed] [Google Scholar]
  • 8.de Rezende CH, Costa-Cruz JM, Gennari-Cardoso ML. Enteroparasitoses em manipuladores de alimentos de escolas públicas em Uberlândia (Minas Gerais), Brasil [Enteroparasitoses in food handlers of the public schools in Uberlândia (Minas Gerais), Brazil] Rev Panam Salud Publica. 1997;2(6):392–397. [PubMed] [Google Scholar]
  • 9.Machado ER, Costa-Cruz JM. Strongyloides stercoralis and other enteroparasites in children at Uberlândia city, state of Minas Gerais, Brazil. Mem Inst Oswaldo Cruz. 1998;93(2):161–164. doi: 10.1590/s0074-02761998000200004. [DOI] [PubMed] [Google Scholar]
  • 10.Coelho LM, Aidar T, Sobrinho, Oliveira SM, Ikegami MT, Yoshizumi AM, Nakamoto AY, Sd Brotto, Felberg S, Maiorano MR. Ovos e larvas de helmintos nos sanitários de pré-escolas municipais de Sorocaba, SP e suas freqüências nas fezes das crianças [Helminth eggs and larvae in restrooms at municipal nursery schools in Sorocaba, SP, Brazil, and their frequency in children feces] Rev Soc Bras Med Trop. 1999;32(6):647–652. doi: 10.1590/s0037-86821999000600006. [DOI] [PubMed] [Google Scholar]
  • 11.Tavares-Dias M, Grandini AA. Prevalence and epidemiological aspects of parasitic infestation in the population of São José da Bela Vista, São Paulo State, Brazil. Rev Soc Bras Med Trop. 1999;32(1):63–65. doi: 10.1590/s0037-86821999000100012. [DOI] [PubMed] [Google Scholar]
  • 12.Uchôa C, Lobo A, Bastos OMP, Matos AD. Intestinal parasitism: prevalence in day-care centers of Niterói city, Rio de Janeiro - Brazil. Rev Inst Adolfo Lutz. 2001;60(2):97–101. [Google Scholar]
  • 13.Iñiguez AM, Vicente AC, Araújo A, Ferreira LF, Reinhard KJ. Enterobius vermicularis: specific detection by amplification of an internal region of 5S ribosomal RNA intergenic spacer and trans-splicing leader RNA analysis. E. vermicularis: specific detection by PCR and SL1 RNA analysis. Exp Parasitol. 2002;102(3-4):218–222. doi: 10.1016/s0014-4894(03)00059-6. [DOI] [PubMed] [Google Scholar]
  • 14.Tashima NT, Simões MJ. Enteroparasitic occurrence in fecal samples analyzed at the University of Western São Paulo-UNOESTE Clinical Laboratory, Presidente Prudente, São Paulo State, Brazil. Rev Inst Med Trop Sao Paulo. 2004;46(5):243–248. doi: 10.1590/s0036-46652004000500002. [DOI] [PubMed] [Google Scholar]
  • 15.Carvalho-Costa FA, Gonçalves AQ, Lassance SL, de Albuquerque CP, Leite JP, Bóia MN. Detection of Cryptosporidium spp and other intestinal parasites in children with acute diarrhea and severe dehydration in Rio de Janeiro. Rev Soc Bras Med Trop. 2007;40(3):346–348. doi: 10.1590/s0037-86822007000300020. [DOI] [PubMed] [Google Scholar]
  • 16.da Silva DF, da Silva RJ, da Silva MG, Sartorelli AC, Rodrigues MA. Parasitic infection of the appendix as a cause of acute appendicitis. Parasitol Res. 2007;102(1):99–102. doi: 10.1007/s00436-007-0735-0. [DOI] [PubMed] [Google Scholar]
  • 17.Barçante TA, Cavalcanti DV, Silva GAV, Lopes PB, Barros RF, Ribeiro GP, et al. Enteroparasitos em crianças matriculadas em creches públicas do Município de Vespasiano, Minas Gerais. Rev Patol Trop. 2008;37(1):33–42. [Google Scholar]
  • 18.Machado ER, Santos DS, Costa-Cruz JM. Enteroparasites and commensals among children in four peripheral districts of Uberlândia, State of Minas Gerais. Rev Soc Bras Med Trop. 2008;41(6):581–585. doi: 10.1590/s0037-86822008000600007. [DOI] [PubMed] [Google Scholar]
  • 19.Machado ER, Souza TS, Costa JM, Costa-Cruz JM. Enteroparasites and commensals among individuals living in rural and urban areas in Abadia dos Dourados, Minas Gerais state, Brazil. Parasitol Latinoam. 2008;63(1-4):34–39. [Google Scholar]
  • 20.Korkes F, Kumagai FU, Belfort RN, Szejnfeld D, Abud TG, Kleinman A, et al. Relationship between intestinal parasitic infection in children and soil contamination in an urban slum. J Trop Pediatr. 2009;55(1):42–45. doi: 10.1093/tropej/fmn038. [DOI] [PubMed] [Google Scholar]
  • 21.Tashima NT, Simões MJ, Leite CQ, Fluminhan A, Nogueira MA, Malaspina AC. Classic and molecular study of Giardia duodenalis in children from a daycare center in the region of Presidente Prudente, São Paulo, Brazil. Rev Inst Med Trop Sao Paulo. 2009;51(1):19–24. doi: 10.1590/s0036-46652009000100004. [DOI] [PubMed] [Google Scholar]
  • 22.Martins LP, Serapião AA, Valenciano RF, Oliveira GT, Santos KJ, Castanho RE. Initial evaluation of some enteroparasitosis prevalence in the community of Palmital, Berilo, MG. Rev Med Minas Gerais. 2009;19(1):26–31. [Google Scholar]
  • 23.Silva LP, Goncalves da Silva RM. Ocorrência de enteroparasitos em centros de educação infantil no município de Patos de Minas, MG, Brasil. Bioscience Journal. 2010:147–151. [Google Scholar]
  • 24.Machado ER, Freitas CVD, Costa-Cruz JM. Strongyloides stercoralis and other enteroparasites in individuals of rural area of Uberlândia, Minas Gerais state, Brazil. Rev Patol Trop. 2010;39(2) [Google Scholar]
  • 25.Moura RGF, Ramos ELP, Colombo MS, de Macedo Aidar FDL, Hernández CG, de Oliveira Silva MB, et al. Prevalence of intestinal parasites in child day care centers: epidemiological significance. Rev Patol Trop. 2017;46(1):75–84. [Google Scholar]
  • 26.Fonseca REPD, Barbosa MCR, Ferreira BR. High prevalence of enteroparasites in children from Ribeirão Preto, São Paulo, Brazil. Rev Bras Enferm. 2017;70(3):566–571. doi: 10.1590/0034-7167-2016-0059. [DOI] [PubMed] [Google Scholar]
  • 27.Oliveira Albuquerque N, Andrade de Souza MA. Análise parasitológica em estudantes com deficiência intelectual e/ou múltipla (o múltiple) Salud (i) Ciencia. 2017;22(7):625–630. [Google Scholar]
  • 28.Valença Barbosa C, de Jesus Batista R, Pereira Igreja R, d'Avila Levy CM, Werneck de Macedo H, Carneiro Santos HL. Distribution of Blastocystis subtypes isolated from humans from an urban community in Rio de Janeiro, Brazil. Parasit Vectors. 2017;10(1):518–518. doi: 10.1186/s13071-017-2458-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 29.Barbosa CV, Barreto MM, Andrade RJ, Sodré F, d'Avila-Levy CM, Peralta JM, Igreja RP, de Macedo HW, Santos HLC. Intestinal parasite infections in a rural community of Rio de Janeiro (Brazil): Prevalence and genetic diversity of Blastocystis subtypes. PLoS One. 2018;13(3):e0193860. doi: 10.1371/journal.pone.0193860. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30.Iasbik AF, De Arruda Pinto OS, Guimarães-Peixoto RPM, De Oliveira Santos T, Fernandes FM, Da Silva LF, et al. Prevalence and transmission of intestinal parasitosis in human beings from Zona da Mata, Minas Gerais, Brazil. Biosci j (Online) 2018;34(3):802–809. [Google Scholar]
  • 31.Eustachio PFP, Avelar LA, Dias JVL, Queiroz DRM, Murta NMG, de Oliveira GHB, et al. Intestinal parasitosis and environmental contamination with helminths and protozoa in a Quilombola community of southeast Brazil. Rev Cubana Med Trop. 2019;71(1):1–13. [Google Scholar]
  • 32.Ferreira CS, Camargo LM, Moitinho ML, de Azevedo RA. Intestinal parasites in Iaualapiti Indians from Xingu Park, Mato Grosso, Brazil. Mem Inst Oswaldo Cruz. 1991;86(4):441–442. doi: 10.1590/s0074-02761991000400012. [DOI] [PubMed] [Google Scholar]
  • 33.Guilherme ALF, De Araujo SM, Teles Pupulim AR, Morais Falavigna DL. Intestinal parasites and commensals of settled populations in three land settlements (Vilas Rurais) of Parana state, Brazil. Acta Sci Health Sci. 2004;26(2):331–336. [Google Scholar]
  • 34.Basso RM, Silva-Ribeiro RT, Soligo DS, Ribacki SI, Callegari-Jacques SM, Zoppas BC. Evolução da prevalência de parasitoses intestinais em escolares em Caxias do Sul, RS [Evolution of the prevalence of intestinal parasitosis among schoolchildren in Caxias do Sul, RS] Rev Soc Bras Med Trop. 2008;41(3):263–268. doi: 10.1590/s0037-86822008000300008. [DOI] [PubMed] [Google Scholar]
  • 35.Silva FS, Paulo ADC, Braga C, Almeida RJ, Galvão VP. Frequency of intestinal parasites in the municipality of Chapadinha, Maranhão, Brazil. Rev Patol Trop. 2010;39(1):63–68. [Google Scholar]
  • 36.Valverde JG, Gomes-Silva A, De Carvalho Moreira CJ, Leles De Souza D, Jaeger LH, Martins PP, et al. Prevalence and epidemiology of intestinal parasitism, as revealed by three distinct techniques in an endemic area in the Brazilian Amazon. Ann Trop Med Parasitol. 2011;105(6):413–424. doi: 10.1179/1364859411Y.0000000034. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 37.Fernandes NS, Guimarães HR, A ACS, Brito VM, Borges EP, Reis MB, et al. Occurrence of intestinal parasites in food handlers working in restaurants of the city of Parnaíba, Piauí-Brazil. Rev Patol Trop. 2014;43(4):459–469. [Google Scholar]
  • 38.Neres-Norberg A, Guerra-Sanches F, Blanco Moreira-Norberg PR, Madeira-Oliveira JT, Santa-Helena AA, Serra-Freire NM. Rev Salud Publica. 6. Vol. 16. Bogota: 2014. Enteroparasitismo en Indígenas Terena en el Estado de Mato Grosso do Sul, Brasil [Intestinal Parasitism in Terena Indigenous People of the Province of Mato Grosso do Sul, Brazil] pp. 859–870. [PubMed] [Google Scholar]
  • 39.Santos CV, Gallina T, Borsuk S, Berne MEA, Villela MM. Enteroparasites and ostomized individuals. Rev Patol Trop. 2014;43(1):79–88. [Google Scholar]
  • 40.Santos J, Duarte ARM, Gadotti G, Lima LM. Intestinal parasites in children at a community creche in Florianópolis, SC, Brazil. Rev Patol Trop. 2014;43(3):332–340. [Google Scholar]
  • 41.Benitez NA, Mareze M, Miura AC, Brunieri DTSC, Ferreira FP, Mitsuka-Breganó R, et al. Abordagem da saúde única na ocorrência de enteroparasitas em humanos de área urbana no norte do Paraná. Arq Ciênc Vet Zool UNIPAR. 2016;19(4):203–208. [Google Scholar]
  • 42.Andrade RS, Albuquerque WA, Miranda FS, Marques BC, Mota LHS, Santos RS, et al. Presence of enteroparasites in the environment and the resident population in a rural community in Santo Antonio de Jesus in the reconcavo da Bahia, Brazil. Rev Patol Trop. 2018;47(1):31–45. [Google Scholar]
  • 43.Zanotto M, Cavagnolli NI, Breda JC, Spada PKWDS, Bortolini GV, Rodrigues AD. Prevalence of intestinal parasites and socioeconomic evaluation of a country town in the Serra Gaucha region, Rio Grande do Sul, Brazil. Rev Patol Trop. 2018;47(1):19–30. [Google Scholar]
  • 44.Monteiro ACS, Soares DA, Diniz SCPOR, Cavalcante UMB, Silva AB, Vianna RPT, et al. Intestinal parasitism and related risk factors for primary school students in João Pessoa, northeast Brazil. Biosci J (Online) 2018;34(4):1062–1072. [Google Scholar]
  • 45.Almeida TMA, Ogawa L, Melo SCCS, Otomura FH. Ocorrência de enteroparasitos em escolares no município de Bandeirantes, Paraná, Brasil. Semina Cienc Biol Saude. 2020;41(1):31–42. [Google Scholar]
  • 46.Ferreira ALC, Carvalho FF, Nihei OK, Nascimento IA, Shimabuku RS, Junior, Fernandes RD, et al. Prevalence of intestinal parasites in children from public preschool in the Triple Border Brazil, Argentina, and Paraguay. ABCS Health Sci. 2021;46:e021205 [Google Scholar]
  • 47.Carvalho LH, Alegranci P, Andrade TSA, Correira NS, Bonacorsi C, Donofrio FC. Medicina. 2 Vol. 55. Ribeirão Preto: 2022. Perfil epidemiológico das enteroparasitoses em pré-escolares e escolares da rede municipal de ensino de Sinop - MT. Online. [Google Scholar]
  • 48.Heukelbach J, Wilcke T, Winter B, Sales de Oliveira FA, Sabóia Moura RC, Harms G, et al. Efficacy of ivermectin in a patient population concomitantly infected with intestinal helminths and ectoparasites. Arzneimittelforschung. 2004;54(7):416–421. doi: 10.1055/s-0031-1296993. [DOI] [PubMed] [Google Scholar]
  • 49.Araujo CF, Fernández CL. Prevalência de parasitoses intestinais na cidade de Eirunepé, Amazonas [Prevalence of intestinal parasitosis in the city of Eirunepé, Amazon] Rev Soc Bras Med Trop. 2005;38(1):69–69. doi: 10.1590/s0037-86822005000100016. [DOI] [PubMed] [Google Scholar]
  • 50.Chavez SEM, Vazquez L, Lopes K, Flores J, Oliveira L, Rizzi L, et al. Levantamento de protozoonoses e verminoses nas sete creches municipais de Uruguaiana, Rio Grande do Sul - Brasil. Rev Bras Anal Clin. 2006;38(1):39–41. [Google Scholar]
  • 51.Monteiro AMC, Silva EF, Almeida KS, Sousa JJN, Mathias LA, Baptista F, et al. Intestinal parasitic infections in children attending day care centers located in peripheral neighborhoods in the municipality of Coari, state of Amazonas, Brazil. Rev Patol Trop. 2009;38(4):284–290. [Google Scholar]
  • 52.Oliveira CLM, Ferreira WA, Vasquez FG, Barbosa MGV. Parasitoses intestinais e fatores socioambientais de uma população da área Periurbana de Manaus - AM. Rev Bras Promoç Saúde. 2010;23(4):307–315. [Google Scholar]
  • 53.Campos CAM, Silva EBO, Campos NWC. Association of enterobiasis and enuresis among children in an orphanage in Natal-RN. Rev Patol Trop. 2011;40(3):247–252. [Google Scholar]
  • 54.Araújo JRO, Cavalcante RMS, Carvalho APM, Neto, Silva KWL, Silva SRG, Ferreira JRS, et al. Frequency of intestinal parasites in patients attended at a university hospital in Maceió, state of Alagoas, Brazil. Biosci J (Online) 2020;36(6):2266–2274. [Google Scholar]
  • 55.Alves SS, Santos JNS, Cayres MAS, Silva NO, Vieira VC, Santos MS. Infecções parasitárias intestinais em crianças e adolescentes na comunidade: aspectos socioeconômicos e higiênico-sanitários. Rev Ciênc Méd Biol. 2021;20(4):624–630. [Google Scholar]
  • 56.Sinhorin GH, Carneiro ACG, Farias BES, de Almeida P, Medeiros-Sousa AR, Melchior LAK, et al. Intestinal parasite infections associated with sociodemographic and seasonal factors in the Western Amazon. Parasitol Res. 2023;122(2):419–423. doi: 10.1007/s00436-022-07736-9. [DOI] [PubMed] [Google Scholar]
  • 57.Aidar T, Sobrinho, Coelho LMDPDS, Oliveira SMD, Martins JDT, Rabello JA, Júnior, Oliveira CRPD, et al. Estudo da freqüência de ovos de helmintos intestinais em sanitários de uso público de Sorocaba, SP. Rev Soc Bras Med Trop. 1995;28:33–37. doi: 10.1590/s0037-86821995000100006. [DOI] [PubMed] [Google Scholar]
  • 58.Borges CA, Costa-Cruz JM, Paula FM. Intestinal parasites inside public restrooms and buses from the city of Uberlândia, Minas Gerais, Brazil. Rev Inst Med Trop São Paulo. 2009;51(4):223–225. doi: 10.1590/s0036-46652009000400009. [DOI] [PubMed] [Google Scholar]
  • 59.Andrade SS, Teodoro LM, Viana DJ, Canuto-Sales EM, Bahia-de-Oliveira GH, Villas Bôas S, et al. Intestinal parasites in public transport buses from the city of Diamantina, Minas Gerais, Brazil. Res Rep Trop Med. 2017;8:59–63. doi: 10.2147/RRTM.S122046. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 60.Silva SRP, Arrosi N, Jesus RS, Reis RS, Rott MB. Intestinal parasites in persons with special needs: prevalence in individuals from institutions in the city of Porto Alegre, Brazil. Rev Patol Trop. 2010;39(2):123–129. [Google Scholar]
  • 61.Nikaido M, Tonani KA, Julião FC, Trevilato TM, Takayanagui AM, Sanches SM, et al. Analysis of bacteria, parasites, and heavy metals in lettuce (Lactuca sativa) and rocket salad (Eruca sativa L.) irrigated with treated effluent from a biological wastewater treatment plant. Biol Trace Elem Res. 2010;134(3):342–351. doi: 10.1007/s12011-009-8477-8. [DOI] [PubMed] [Google Scholar]
  • 62.Porto LP, Cavagnolli NI, Reis DS, Spada PKWDS, Rodrigues AD. Prevalence of parasitic infections in restaurant employees in Caxias do Sul, RS, Brazil. Rev Patol Trop. 2016;45(1):115–120. [Google Scholar]
  • 63.Instituto Brasileiro de Geografia e Estatística . Censo: falta de endereço em favelas dificulta registro de domicílios. Agência Brasil - Data Favela 2022. Jul 11, 2023. [Google Scholar]

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