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. 2023 Oct 6;9:36. doi: 10.1186/s40959-023-00187-w

Table 2.

Death and Major Adverse Cardiac Event (MACE) by group and viral variant

CVD (-) CVD ( +) Cardioonc (-) Cardioonc ( +) Total p-value*
Early SARS-CoV-2 Total cases 217,282 22,137 50,212 737 290,368
Death (%) 11.1 22.8 26.2 37.6 14.6 < 0.001
MACE (%) 43.1 46.5 47.3 54.5 44.1 < 0.001
Alpha Total cases 51,579 9923 8870 324 70,696
Death (%) 6.9 19.0 17.3 30.9 10.0 < 0.001
MACE (%) 38.1 41.8 37.1 49.4 38.6 < 0.001
Delta Total cases 34,064 6440 5682 262 70,696
Death (%) 5.5 16.7 13.8 22.5 8.2 < 0.001
MACE (%) 36.2 37.0 33.0 40.8 36.0 < 0.001
Omicron Total cases 6161 2166 1057 68 9452
Death (%) 3.7 14.0 8.9 20.6 6.8 < 0.001
MACE (%) 33.8 34.9 25.5 35.3 33.2 < 0.001

CVD (-) Cardiovascular Disease and SARS-CoV-2 negative, Cardioonc (-) Cardiovascular Disease and Active Cancer and SARS-CoV-2 negative, Cardioonc ( +) Cardiovascular Disease and Active Cancer and SARS-CoV-2 positive, CVD ( +) Cardiovascular Disease and SARS-CoV-2 positive

*Chi-square test with p-values was used to assess the proportions among four different cohorts