The following Circulation article is being retracted:
Doser TA, Tuerdi S, Thomas DP, Epstein PN, Li SY, Ren J. Transgenic overexpression of aldehyde dehydroge-nase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. Circulation. 2009;119:1941–1949. DOI: 10.1161/CIRCULATIONAHA.108.823799
Following a recent examination by the University of Wyoming under the direction of the HHS Office of Research Integrity, the University of Wyoming found evidence of data irregularities and image reuse in Figures 1 and 6 that significantly affect the results and conclusions reported in the manuscript. Specifically, the following irregularities were found:
In Figure 1C, β-actin bands appear to be duplicated and used for controls for brain and heart samples.
In Figure 6, β-actin bands of Figure 6B appear to be duplicated and reported as GATA4 in Figure 6E.
The editors are retracting this article based on the findings of the university examination and in agreement with the University of Wyoming.