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. 2023 Oct 10;13:17123. doi: 10.1038/s41598-023-44342-w

Author Correction: Positive selection acts on regulatory genetic variants in populations of European ancestry that affect ALDH2 gene expression

Helmut Schaschl 1,, Tobias Göllner 1, David L Morris 2
PMCID: PMC10564712  PMID: 37816817

Correction to: Scientific Reports https://doi.org/10.1038/s41598-022-08588-0, published online 16 March 2022

The original version of this Article contained a repeated error, where gene name “SH2B3” was incorrectly given as “SH2B2”. As a result of this error, in the Introduction,

“This region, approximately 0.6 Mbp in size (according to the human reference genome), encompasses in addition to ALDH2 the genes CUX2, FAM109A, SH2B2, ATXN2, BRAP, ACAD10 and MAPKAPK5, as well as the uncharacterized transcript ENST00000546840.3 (UniProt F8VP50—Aldedh domain-containing protein), which partially overlaps with the genes ACAD10 and ALDH2. High FST values at linked sites at the ALDH2 locus point to some form of selection for this genomic region36.”

now reads:

“This region, approximately 0.6 Mbp in size (according to the human reference genome), encompasses in addition to ALDH2 the genes CUX2, FAM109A, SH2B3, ATXN2, BRAP, ACAD10 and MAPKAPK5, as well as the uncharacterized transcript ENST00000546840.3 (UniProt F8VP50—Aldedh domain-containing protein), which partially overlaps with the genes ACAD10 and ALDH2. High FST values at linked sites at the ALDH2 locus point to some form of selection for this genomic region36.”

And, in the Results section, under the subheading ‘Positive selection acts on regulatory variants of ALDH2’,

“We also obtained cis-eQTLs (1970 in total) for the other protein-coding genes located in this genomic region (CUX2, FAM109A, SH2B2, ATXN2, BRAP, ACAD10, MAPKAPK5) (Supplementary Table 3).”

now reads:

“We also obtained cis-eQTLs (1970 in total) for the other protein-coding genes located in this genomic region (CUX2, FAM109A, SH2B3, ATXN2, BRAP, ACAD10, MAPKAPK5) (Supplementary Table 3).”

The original Article has been corrected.


Articles from Scientific Reports are provided here courtesy of Nature Publishing Group

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