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. 2023 Jul 14;46(5):1832–1848. doi: 10.1007/s10753-023-01844-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Foamy microglia with unique transcriptomes were associated with inflammation and phagocytosis. a Experimental schematic of RNA-sequencing (RNA-seq) in fluorescently activated cell sorting (FACS)-isolated BODIPY-high / BODIPY-low microglia from ischemic hemispheres of MCAO 3d mice. Six hemispheres were pooled into one sample. n = 3/group. b Scatter plot showing differentially expressed genes (DEGs) between BODIPY-high microglia and BODIPY-low microglia. |logFC (fold change)|> 1, p value < 0.05. c, d GO c and KEGG d enrichment analysis of DEGs between BODIPY-high microglia and BODIPY-low microglia.