Abstract
The streptomycin-producing capacity of submerged cultures of Streptomyces griseus 107 was nearly lost during repeated transfers on synthetic nutrient medium. This effect did not occur on the same nutrient medium from which Fe++ was omitted. The physiological reason for this effect was discussed from the point of the relationship of iron-containing porphyrin enzymes to the process of streptomycin biosynthesis.
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Selected References
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- CHESTERS C. G. C., ROLINSON G. N. Trace elements and streptomycin production. J Gen Microbiol. 1951 Aug;5(3):559–565. doi: 10.1099/00221287-5-3-559. [DOI] [PubMed] [Google Scholar]
- FERGUSON J. H., HUANG H. T., DAVISSON J. W. Stimulation of streptomycin production by a series of synthetic organic compounds. Appl Microbiol. 1957 Sep;5(5):339–343. doi: 10.1128/am.5.5.339-343.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PERLMAN D., GREENFIELD R. B., Jr, O'BRIEN E. Degeneration of a Streptomyces griseus mutant on repeated transfer. Appl Microbiol. 1954 Jul;2(4):199–202. doi: 10.1128/am.2.4.199-202.1954. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WILLIAMS A. M., McCOY E. Degeneration and regeneration of Streptomyces griseus. Appl Microbiol. 1953 Nov;1(6):307–313. doi: 10.1128/am.1.6.307-313.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]