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. 1963 Mar;11(2):78–83. doi: 10.1128/am.11.2.78-83.1963

Antifungal Activity of Ring Poly-Chlorinated Pyrimidines: Structure Activity Relationships

Herman Gershon 1, Raulo Parmegiani 1
PMCID: PMC1057946  PMID: 13960594

Abstract

A total of 48 ring chlorinated pyrimidines was screened against strains of five fungi by the disc-plate method, in liquid culture, and for activity of the vapors of the compounds. Correlations of the results obtained by the three methods were made, and structure to activity relationships were discussed. The outstanding members of this series were found to be 2,4,5-trichloropyrimidine, 4,5,6-trichloropyrimidine, and 2-chloromethyl-4,5,6-trichloropyrimidine, in this screening system.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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