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. 1963 Jul;11(4):371–376. doi: 10.1128/am.11.4.371-376.1963

Preservation by Freeze-Drying and the Stability of Virulence of Salmonella typhimurium

Ellen M Simon 1, K L Stahl 1, J B Wilson 1
PMCID: PMC1058006  PMID: 13977458

Abstract

Differences in the ability to withstand freeze-drying were demonstrated among strains of Salmonella typhimurium. On the average, the number of viable cells in freeze-dried cultures stored at 5 C for 12 to 18 months was approximately one half as large as that found 24 hr after freeze-drying. The viability in samples stored at higher temperatures declined rapidly and was correlated with the dryness of the sample. The virulence for mice of three strains of S. typhimurium did not change appreciably when samples were kept for 1 or 2 years as freeze-dried samples stored at 5 C, or as agar cultures stored at 5 C or at room temperature.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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