Skip to main content
Applied Microbiology logoLink to Applied Microbiology
. 1964 Mar;12(2):132–137. doi: 10.1128/am.12.2.132-137.1964

Inactivation of Viruses by Benzalkonium Chloride

J A Armstrong 1,1, E J Froelich 1
PMCID: PMC1058082  PMID: 4288740

Abstract

Benzalkonium chloride (as Roccal or Zephiran) was found to inactivate influenza, measles, canine distemper, rabies, fowl laryngotracheitis, vaccinia, Semliki Forest, feline pneumonitis, meningopneumonitis, and herpes simplex viruses after 10 min of exposure at 30 C or at room temperature. Poliovirus and encephalomyocarditis virus were not inactivated under the same conditions. It was concluded that all viruses tested were sensitive except members of the picorna group. The literature was reviewed.

Full text

PDF
132

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BUCCA M. A. The effect of various chemical agents on eastern equine encephalomyelitis virus. J Bacteriol. 1956 Apr;71(4):491–492. doi: 10.1128/jb.71.4.491-492.1956. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CARTWRIGHT S. F., THORNE H. V. Some applications of detergents to the study of the virus of foot-and-mouth disease. J Gen Microbiol. 1959 Feb;20(1):61–77. doi: 10.1099/00221287-20-1-61. [DOI] [PubMed] [Google Scholar]
  3. CELIKER A., GILLESPIE J. H. The effect of temperature pH, and certain chemicals on egg-cultivated distemper virus. Cornell Vet. 1954 Apr;44(2):276–280. [PubMed] [Google Scholar]
  4. DEAN D. J., BAER G. M., THOMPSON W. R. Studies on the local treatment of rabies-infected wounds. Bull World Health Organ. 1963;28(4):477–486. [PMC free article] [PubMed] [Google Scholar]
  5. ESPMARK A., SALENSTEDT C. R. [Viruses and invert soaps]. Nord Med. 1960 Sep 22;64:1194–1196. [PubMed] [Google Scholar]
  6. GONNERT R., BOCK M. Zur Resistenz von Viren. Z Hyg Infektionskr. 1955;141(1):60–63. [PubMed] [Google Scholar]
  7. NOLL H., YOUNGNER J. S. Virus-lipid interactions. II. The mechanism of adsorption of lipophilic viruses to water-insoluble polar lipids. Virology. 1959 Jul;8(3):319–343. doi: 10.1016/0042-6822(59)90033-9. [DOI] [PubMed] [Google Scholar]
  8. SCHULZ-EHLBECK H. W. Beitrag zur Frage der Virusinaktivierung. Klin Wochenschr. 1953 Jun 1;31(21-22):527–527. doi: 10.1007/BF01477590. [DOI] [PubMed] [Google Scholar]
  9. WIKTOR T. J., KOPROWSKI H. [Local action of various drugs on rabies infection in mice]. Bull World Health Organ. 1963;28(4):487–494. [PMC free article] [PubMed] [Google Scholar]

Articles from Applied Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES