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. 1966 Nov;14(6):934–939. doi: 10.1128/am.14.6.934-939.1966

Microbial Detoxification of Aflatoxin

A Ciegler 1, E B Lillehoj 1, R E Peterson 1, H H Hall 1
PMCID: PMC1058446  PMID: 16349699

Abstract

Yeasts, molds, bacteria, actinomycetes, algae, and fungal spores were screened for their ability to degrade aflatoxin. Some molds and mold spores partially transformed aflatoxin B1 to new fluorescing compounds. Only one of the bacteria, Flavobacterium (aurantiacum?) NRRL B-184, removed aflatoxin from solution. Both growing and resting cells of B-184 took up toxin irreversibly. Toxin-contaminated milk, oil, peanut butter, peanuts, and corn were completely detoxified, and contaminated soybean was partially detoxified by addition of B-184. Duckling assays showed that detoxification of aflatoxin solutions by B-184 was complete, with no new toxic products being formed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BUTLER W. H. ACUTE TOXICITY OF AFLATOXIN B-1 IN RATS. Br J Cancer. 1964 Dec;18:756–762. doi: 10.1038/bjc.1964.87. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Butler W. H., Clifford J. I. Extraction of aflatoxin from rat liver. Nature. 1965 Jun 5;206(988):1045–1046. doi: 10.1038/2061045a0. [DOI] [PubMed] [Google Scholar]
  3. DE IONGH H., VLES R. O., VAN PELTJ MILK OF MAMMALS FED AN AFLATOXIN-CONTAINING DIET. Nature. 1964 May 2;202:466–467. doi: 10.1038/202466a0. [DOI] [PubMed] [Google Scholar]
  4. DICKENS F. CARCINOGENIC LACTONES AND RELATED SUBSTANCES. Br Med Bull. 1964 May;20:96–101. doi: 10.1093/oxfordjournals.bmb.a070324. [DOI] [PubMed] [Google Scholar]
  5. Gabliks J., Schaeffer W., Friedman L., Wogan G. Effect of Aflatoxin B(1) on Cell Cultures. J Bacteriol. 1965 Sep;90(3):720–723. doi: 10.1128/jb.90.3.720-723.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. HAYNES W. C., WICKERHAM L. J., HESSELTINE C. W. Maintenance of cultures of industrially important microorganisms. Appl Microbiol. 1955 Nov;3(6):361–368. doi: 10.1128/am.3.6.361-368.1955. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HODGES F. A., ZUST J. R., SMITH H. R., NELSON A. A., ARMBRECHT B. H., CAMPBELL A. D. MYCOTOXINS: AFLATOXIN ISOLATED FROM PENICILLIUM PUBERULUM. Science. 1964 Sep 25;145(3639):1439–1439. doi: 10.1126/science.145.3639.1439. [DOI] [PubMed] [Google Scholar]
  8. JUHASZ S., GRECZI E. EXTRACTS OF MOULD-INFECTED GROUNDNUT SAMPLES IN TISSUE CULTURE. Nature. 1964 Aug 22;203:861–862. doi: 10.1038/203861a0. [DOI] [PubMed] [Google Scholar]
  9. VEZINA C., SEHGAL S. N., SINGH K. Transformation of steroids by spores of microorganisms. I. Hydroxylation of progesterone by conidia of Aspergillus ochraceus. Appl Microbiol. 1963 Jan;11:50–57. doi: 10.1128/am.11.1.50-57.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. de IONGH, BEERTHUIS R. K., VLES R. O., BARRETT C. B., ORD W. O. Investigation of the factor in groundnut meal responsible for "turkey X disease". Biochim Biophys Acta. 1962 Dec 17;65:548–551. [PubMed] [Google Scholar]

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