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. 2023 May 31;48(13):1840–1848. doi: 10.1038/s41386-023-01609-0

Fig. 3. Acute autonomic effects of 100 µg lysergic acid diethylamide (LSD), 100 mg 3,4-methylenedioxymethamphetamine (MDMA), and the LSD + MDMA combination (100 µg+100 mg) over time.

Fig. 3

LSD, MDMA, and the LSD + MDMA combination increased blood pressure, heart rate, and body temperature compared with placebo. MDMA alone and the LSD + MDMA combination increased blood pressure and heart rate more compared with LSD alone. The substances were administered at t = 0 h. The data are expressed as the mean ± SEM in 24 subjects. The corresponding maximal responses and statistics are shown in Table 1.