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. 2023 Oct 10;101(15):e1483–e1494. doi: 10.1212/WNL.0000000000207701

Figure 4. Defining the Hub of the Essential Tremor Network.

Figure 4

(A) Sensitive to ET: Coordinate network mapping found the cerebellum to be most strongly connected to coordinates of brain abnormality in ET (thresholded at 90%, connected to 13/14 study-specific seeds); (B) Specific to ET: A specificity analysis revealed voxels with significantly greater functional connectivity to coordinates of abnormality in essential tremor than control disorders (p < 0.05). (C) Conjunction (network hub of ET): A conjunction analysis identified a network hub that was both sensitive and specific to essential tremor.