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. 1995 Feb;49(1):54–60. doi: 10.1136/jech.49.1.54

Opiates or cocaine: mortality from acute reactions in six major Spanish cities. State Information System on Drug Abuse (SEIT) Working Group.

J Sánchez 1, B Rodríguez 1, L de la Fuente 1, G Barrio 1, J Vicente 1, J Roca 1, L Royuela 1
PMCID: PMC1060075  PMID: 7707007

Abstract

STUDY OBJECTIVE--To describe temporal and geographical variations in mortality from acute reactions to opiates or cocaine and the demographic and toxicological characteristics of persons who died from these in major Spanish cities between 1983 and 1991. DESIGN--Descriptive study. Data were obtained retrospectively from pathologists' reports. SETTING--Cities of Madrid, Barcelona, Valencia, Seville, Zaragoza, and Bilbao. SUBJECTS--Deaths from acute reactions to opiates or cocaine were defined as those in which pathologists' reports did not indicate any other cause of death and in which evidence was found of recent consumption of these drugs. MAIN RESULTS--The mortality rate from acute reactions to opiate/cocaine per 100,000 population in the six cities as a whole rose from 1.2 in 1983 to 8.2 in 1991. Average annual rates for the whole period ranged from 1.7 in Seville to 4.9 in Barcelona. The male/female rates ratio was 5.9:1. The mean age of persons who died rose from 25.1 years in 1983 to 28 years in 1991. In more than 90% of the cases in whom toxicological tests were undertaken opiates were detected, and the proportion in which benzodiazepines or cocaine were detected increased during the period studied. CONCLUSIONS--Between 1983 and 1991 mortality from acute reactions to opiates/cocaine rose dramatically in major Spanish cities and significant differences in mortality between cities were found. Deaths were concentrated among men and young people. Acute drug reactions became one of the leading causes of death in persons 15-39 years of age, representing 11.1% of mortality from all causes in 1988 for this age group. Future studies should examine the relationship between the temporal and geographical variations in this type of mortality and various personal, environmental and social factors.

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Selected References

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  1. Alexander M. Surveillance of heroin-related deaths in Atlanta, 1971 to 1973. JAMA. 1974 Aug 5;229(6):677–678. [PubMed] [Google Scholar]
  2. Barrio Anta G., Vicente Orta J., Bravo Portela M. J., de la Fuente de Hoz L. The epidemiology of cocaine use in Spain. Drug Alcohol Depend. 1993 Dec;34(1):45–57. doi: 10.1016/0376-8716(93)90045-r. [DOI] [PubMed] [Google Scholar]
  3. Barrio G., de la Fuente L., Camí J. El consumo de drogas en España y su posición en el contexto europeo. Med Clin (Barc) 1993 Sep 25;101(9):344–355. [PubMed] [Google Scholar]
  4. Cherubin C., McCusker J., Baden M., Kavaler F., Amsel Z. Epidemiology of death in narcotic addicts. Am J Epidemiol. 1972 Jul;96(1):11–22. doi: 10.1093/oxfordjournals.aje.a121428. [DOI] [PubMed] [Google Scholar]
  5. Domingo A., Antó J. M., Cami J. Epidemiological surveillance of opioid-related episodes in an emergency room of Barcelona, Spain (1979-1989) Br J Addict. 1991 Nov;86(11):1459–1466. doi: 10.1111/j.1360-0443.1991.tb01731.x. [DOI] [PubMed] [Google Scholar]
  6. Escobedo L. G., Ruttenber A. J., Agocs M. M., Anda R. F., Wetli C. V. Emerging patterns of cocaine use and the epidemic of cocaine overdose deaths in Dade County, Florida. Arch Pathol Lab Med. 1991 Sep;115(9):900–905. [PubMed] [Google Scholar]
  7. Finkle B. S., McCloskey K. L., Goodman L. S. Diazepam and drug-associated deaths. A survey in the United States and Canada. JAMA. 1979 Aug 3;242(5):429–434. [PubMed] [Google Scholar]
  8. Frischer M., Bloor M., Goldberg D., Clark J., Green S., McKeganey N. Mortality among injecting drug users: a critical reappraisal. J Epidemiol Community Health. 1993 Feb;47(1):59–63. doi: 10.1136/jech.47.1.59. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Greene M. H., Luke J. L., Dupont R. L. Opiate "overdose" deaths in the District of Columbia. I. Heroin-related fatalities. Med Ann Dist Columbia. 1974 Apr;43(4):175–181. [PubMed] [Google Scholar]
  10. Harlow K. C. Patterns of rates of mortality from narcotics and cocaine overdose in Texas, 1976-87. Public Health Rep. 1990 Sep-Oct;105(5):455–462. [PMC free article] [PubMed] [Google Scholar]
  11. Huber D. H., Stivers R. R., Howard L. B. Heroin-overdose deaths in Atlanta. An epidemic. JAMA. 1974 Apr 15;228(3):319–322. [PubMed] [Google Scholar]
  12. Janssen W., Trübner K., Püschel K. Death caused by drug addiction: a review of the experiences in Hamburg and the situation in the Federal Republic of Germany in comparison with the literature. Forensic Sci Int. 1989 Dec;43(3):223–237. doi: 10.1016/0379-0738(89)90150-3. [DOI] [PubMed] [Google Scholar]
  13. Kandel D. B. The social demography of drug use. Milbank Q. 1991;69(3):365–414. [PubMed] [Google Scholar]
  14. Kringsholm B. Deaths among drug addicts in Denmark in 1968-1986. Forensic Sci Int. 1988 Jul-Aug;38(1-2):139–149. doi: 10.1016/0379-0738(88)90017-5. [DOI] [PubMed] [Google Scholar]
  15. Marti Amengual G., Reig Blanch R., Sanz Gallen P., Garrido Morales P., Font Riera G., Corbella Corbella J. Deaths from poisoning in Barcelona (Spain), 1986-1989. Rev Epidemiol Sante Publique. 1992;40(2):102–107. [PubMed] [Google Scholar]
  16. McKelway R., Vieweg V., Westerman P. Sudden death from acute cocaine intoxication in Virginia in 1988. Am J Psychiatry. 1990 Dec;147(12):1667–1669. doi: 10.1176/ajp.147.12.1667. [DOI] [PubMed] [Google Scholar]
  17. Pollock D. A., Holmgreen P., Lui K. J., Kirk M. L. Discrepancies in the reported frequency of cocaine-related deaths, United States, 1983 through 1988. JAMA. 1991 Oct 23;266(16):2233–2237. [PubMed] [Google Scholar]
  18. Reig P., Sanz P., Martí G., Corbella J. Opioid-related deaths in Barcelona 1981-86. Lancet. 1987 Aug 29;2(8557):508–509. doi: 10.1016/s0140-6736(87)91813-7. [DOI] [PubMed] [Google Scholar]
  19. Rezza G., Dorrucci M., Filibeck U., Serafin I. Estimating the trend of the epidemic of drug use in Italy, 1985-89. Br J Addict. 1992 Dec;87(12):1643–1648. doi: 10.1111/j.1360-0443.1992.tb02677.x. [DOI] [PubMed] [Google Scholar]
  20. Ruttenber A. J., Luke J. L. Heroin-related deaths: new epidemiologic insights. Science. 1984 Oct 5;226(4670):14–20. doi: 10.1126/science.6474188. [DOI] [PubMed] [Google Scholar]
  21. Shai D., Aptekar L. Factors in mortality by drug dependence among Puerto Ricans in New York City. Am J Drug Alcohol Abuse. 1990;16(1-2):97–107. doi: 10.3109/00952999009001575. [DOI] [PubMed] [Google Scholar]
  22. da Matta Chasin A. A., Mídio A. F. Cocaine-related problems in the city of São Paulo, 1982-1986. Bull Narc. 1989;41(1-2):99–101. [PubMed] [Google Scholar]

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