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. 2023 Oct 13;11(10):2778. doi: 10.3390/biomedicines11102778

Figure 5.

Figure 5

Imbalance in relative and absolute numbers of peripheral blood Tc1, Tc2, Tc17 and double-positive Tc17.1 cells in patients with pSS. Scatter plots (A–D) and (E–H): Tc1 (CCR6−CXCR3+), Tc2 (CCR6−CXCR3−), Tc17 (CCR6+CXCR3−) and double-positive Tc17.1 (CCR6+CXCR3+) frequencies, respectively. Scatter plots (A–D): the relative numbers of Tc1, Tc2, Tc17 and Tc17.1 within total CD8+ T cell subset. Scatter plots (E–H): Tc1, Tc2, Tc17 and Tc17.1 concentrations (number of cells per 1 μL of peripheral whole blood). Black circles denote patients with Sjögren’s syndrome (pSS, n = 34); white circles denote healthy control (HC, n = 34). Each data point represents individual subjects, and horizontal bars depict the group medians and quartile ranges (med (Q25; Q75)). The statistical analysis was performed using the Mann–Whitney U test.