Abstract
STUDY OBJECTIVE--To test the hypothesis that children born to mothers living near the sea are at increased risk of limb reduction defects. DESIGN--Descriptive data analysis. SETTING--The northern health region of England. PATIENTS--All children born between 1 January 1985 and 31 December 1992 in the northern region of England with isolated limb reduction defects. MAIN RESULTS--The birth prevalence of isolated limb reduction defects was not affected by the distance the mother lived from the sea. There was some evidence of space-time clustering, but there was no evidence of statistically significant variation in the occurrence of the condition with sex, time of birth (monthly or yearly), or county of birth. CONCLUSIONS--There is no evidence that children born to mothers living near the sea are at increased risk of limb reduction defects.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Botting B. J. Limb reduction defects and coastal areas. Lancet. 1994 Apr 23;343(8904):1033–1034. doi: 10.1016/s0140-6736(94)90152-x. [DOI] [PubMed] [Google Scholar]
- Castilla E. E., da Graca Dutra M. Limb reduction defects and coastal areas. Lancet. 1994 Apr 23;343(8904):1034–1034. [PubMed] [Google Scholar]
- Froster U. G., Baird P. A. Upper limb deficiencies and associated malformations: a population-based study. Am J Med Genet. 1992 Dec 1;44(6):767–781. doi: 10.1002/ajmg.1320440611. [DOI] [PubMed] [Google Scholar]
- Ireland M., Burn J. Cornelia de Lange syndrome--photo essay. Clin Dysmorphol. 1993 Apr;2(2):151–160. [PubMed] [Google Scholar]
- Mastroiacovo P., Botto L., Fusco D., Rosano A., Scarano G. Limb reduction defects and coastal areas. Lancet. 1994 Apr 23;343(8904):1034–1035. [PubMed] [Google Scholar]