Skip to main content
PMC home page
Archives of Disease in Childhood. Fetal and Neonatal Edition logoLink to Archives of Disease in Childhood. Fetal and Neonatal Edition
. 1994 Mar;70(2):F84–F89. doi: 10.1136/fn.70.2.f84

Neonatal outcome after pregnancy complicated by abnormal velocity waveforms in the umbilical artery.

M McDonnell 1, V Serra-Serra 1, G Gaffney 1, C W Redman 1, P L Hope 1
PMCID: PMC1061006  PMID: 8154919

Abstract

The neonatal outcome of 61 infants born after pregnancies complicated by absent or reversed end diastolic flow velocities (AREDFV) in the fetal umbilical artery was compared with that of 61 controls matched for gestational age born after high risk pregnancies with documented forward end diastolic flow velocities (EDFV). The AREDFV group was significantly more growth retarded, had lower platelet counts at birth, and were more likely to become significantly thrombocytopenic in the first week after birth. Owing to concerns about the possible increased risk of necrotising enterocolitis in newborn infants after AREDFV, this group was started on enteral feeds later and was more likely to receive parenteral nutrition than the EDFV group. Seven infants with AREDFV and one control infant developed necrotising enterocolitis.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brar H. S., Platt L. D. Reverse end-diastolic flow velocity on umbilical artery velocimetry in high-risk pregnancies: an ominous finding with adverse pregnancy outcome. Am J Obstet Gynecol. 1988 Sep;159(3):559–561. doi: 10.1016/s0002-9378(88)80007-3. [DOI] [PubMed] [Google Scholar]
  2. Cameron A. D., Nicholson S. F., Nimrod C. A., Harder J. R., Davies D. M. Doppler waveforms in the fetal aorta and umbilical artery in patients with hypertension in pregnancy. Am J Obstet Gynecol. 1988 Feb;158(2):339–345. doi: 10.1016/0002-9378(88)90151-2. [DOI] [PubMed] [Google Scholar]
  3. Dawes G. S., Redman C. W., Smith J. H. Improvements in the registration and analysis of fetal heart rate records at the bedside. Br J Obstet Gynaecol. 1985 Apr;92(4):317–325. doi: 10.1111/j.1471-0528.1985.tb01103.x. [DOI] [PubMed] [Google Scholar]
  4. Hackett G. A., Campbell S., Gamsu H., Cohen-Overbeek T., Pearce J. M. Doppler studies in the growth retarded fetus and prediction of neonatal necrotising enterocolitis, haemorrhage, and neonatal morbidity. Br Med J (Clin Res Ed) 1987 Jan 3;294(6563):13–16. doi: 10.1136/bmj.294.6563.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Malcolm G., Ellwood D., Devonald K., Beilby R., Henderson-Smart D. Absent or reversed end diastolic flow velocity in the umbilical artery and necrotising enterocolitis. Arch Dis Child. 1991 Jul;66(7 Spec No):805–807. doi: 10.1136/adc.66.7_spec_no.805. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Meberg A. Transitory thrombocytopenia in newborn mice after intrauterine hypoxia. Pediatr Res. 1980 Sep;14(9):1071–1073. doi: 10.1203/00006450-198009000-00010. [DOI] [PubMed] [Google Scholar]
  7. Trudinger B. J., Giles W. B., Cook C. M., Bombardieri J., Collins L. Fetal umbilical artery flow velocity waveforms and placental resistance: clinical significance. Br J Obstet Gynaecol. 1985 Jan;92(1):23–30. doi: 10.1111/j.1471-0528.1985.tb01044.x. [DOI] [PubMed] [Google Scholar]
  8. Yudkin P. L., Aboualfa M., Eyre J. A., Redman C. W., Wilkinson A. R. New birthweight and head circumference centiles for gestational ages 24 to 42 weeks. Early Hum Dev. 1987 Jan;15(1):45–52. doi: 10.1016/0378-3782(87)90099-5. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood Fetal and Neonatal edition are provided here courtesy of BMJ Publishing Group

RESOURCES