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Gene expression of antioxidant-related molecular biomarkers in EA.hy926 cells treated with ipconazole at 20 and 50 µM or DMSO (0.1%) as a carrier control.
| Gene | Control | Vehicle (Veh) | Ipconazole | |
|---|---|---|---|---|
| 20 µM | 50 µM | |||
| Fold Change | ||||
| NRF2 | 1.00 | 0.98 | 0.98 | 0.56 ** |
| SOD | 1.00 | 1.06 | 0.92 | 0.90 |
| GPx | 1.00 | 0.97 | 0.97 | 0.45 *** |
Data for gene expression represent fold change mean. ** p < 0.01 or *** p < 0.001 compared to vehicle, for three independent experiments. The green color represents down-regulation.
