Table 2:

Laboratory results before and after treatment with intramuscular injections of vitamin B₁₂ for severe vitamin B₁₂ deficiency presenting as pseudo-thrombotic microangiopathy

Investigation	Reference range	Day since admission
		Day 1	Day 2	Day 3*	Day 4	Day 5	Day 7	Day 35
Hemoglobin, g/L	135–175	45	103†	71	71	75	79	120
MCV, fL	80–100	111	93.1	94.4	92.5	96.3	98.8	89
Platelets, × 109/L	150–400	68	26	19	16	13	54	184
Leukocytes, × 109/L	4–11	2.9	2	2	2.8	2	4	3.7
Unconjugated bilirubin, μmol/L	0–12	58	50.7	51	55
Lactate dehydrogenase, U/L	110–230	> 4500	4424			> 2000‡	1308	155
d-dimer, ng/mL	< 500		40 052	22 036	38 392	2875	1396	304
INR	0.9–1.2	1.4	1.2	1.3	1.3	1.3	1.4	1.1
Vitamin B12, pmol/L	138–652		< 117					404

Note: INR = international normalized ratio, MCV = mean corpuscular volume.

^*First dose of intramuscular vitamin B₁₂ given on day 3 of hospital admission.

^†After transfusion of 4 units packed red blood cells.

^‡Laboratory reported > 2000 U/L and not the exact value.