Skip to main content
. Author manuscript; available in PMC: 2023 Nov 14.
Published in final edited form as: Biochemistry. 2020 Feb 11;59(7):831–835. doi: 10.1021/acs.biochem.9b01092

Figure 1.

Figure 1.

Schematic view of TSID and FBDD in enzyme inhibitor design. (A) TSID designs inhibitors after elucidation of the transition state structure. (B) FBDD identifies and tailors the binding fragments to generate inhibitors.