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. 2023 Oct 18;26(11):108243. doi: 10.1016/j.isci.2023.108243

Figure 2.

Figure 2

Characterization of VP-LDCVs trafficking properties under basal conditions

(A) Single-frame image from a 2-photon time series capture of VP-LDCV movement in an apical dendrite (top) and an axon (bottom) of a VP neuron, showing both the raw image (left) and the Imaris analysis overlay (right). Scale bars: 2 μm.

(B) Violin plot showing the mean VP-LDCV diameter.

(C) Summary of directionality of all tracked LDCVs under baseline conditions. The incidence of LDCVs traveling anterogradely in axons is statistically higher than that in dendrites (∗∗∗p < 0.003, chi-squared test). Numbers below each group represent n values (LDCVs).

(D) Violin plots of mean (left) and max (right) speeds of VP-LDCVs. ∗∗∗∗p < 0.0001, one way ANOVA, Šidák multiple comparisons test.

(E) Mean speed density distribution of VP-LDCVs traveling in retrograde and anterograde direction. Numbers below each group represent n values (LDCVs).