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. 2023 Nov 23;16:302. doi: 10.1186/s12920-023-01742-1

Correction: Polygenic risk for triglyceride levels in the presence of a high impact rare variant

Shengjie Ying 1,2,3, Tracy Heung 3,4, Bhooma Thiruvahindrapuram 5, Worrawat Engchuan 5, Yue Yin 5, Christina Blagojevic 3, Zhaolei Zhang 6,7,8, Robert A Hegele 2, Ryan K C Yuen 5,6, Anne S Bassett 1,3,4,9,10,
PMCID: PMC10666445  PMID: 37996907

Correction: BMC Med Genomics 16, 281 (2023)

https://doi.org/10.1186/s12920-023-01717-2

Following publication of the original article [1], the authors reported errors in Table 1. The first heading of the table should read “Continuous variables” and not “Categorical variables”. The correct table is given in this correction article. The original article [1] has been corrected.

Table 1.

Lipid and other phenotypic/clinical variables, and sex effects, in adults with a 22q11.2 microdeletion

Continuous variables
Total sample Males Females
n Mean SD n Mean SD n Mean SD
Lipid levels
 TG (mmol/L)a 149 1.92 1.18 74 2.25 1.37 75 1.60 0.85
 HDLC (mmol/L) 150 1.15 0.35 75 0.99 0.28 75 1.31 0.33
 LDLC (mmol/L) 148 2.71 0.87 73 2.67 0.86 75 2.75 0.88
 LDLC statin-adjusted (mmol/L)b 148 2.81 0.93 73 2.74 0.85 75 2.88 0.99
 TC (mmol/L) 151 4.72 0.98 76 4.64 0.98 75 4.80 0.99
 TC statin-adjusted (mmol/L)b 151 4.84 1.06 76 4.74 1.02 75 4.94 1.09
Other clinical/demographic variables
 BMI (kg/m2) 151 30.29 7.39 76 29.82 7.36 75 30.77 7.44
 Agec 151 35.66 11.2 76 34.92 11.51 75 36.42 10.9
Categorical variables
Total sample (n = 151) Males (n = 76) Females (n = 75)
n % n % n %
 Mild-moderate HTGa,d 67 45.0 45 60.8 22 29.3
Other clinical/demographic variables
 On statin medication 16 10.6 7 9.2 9 12.0
 Type 2 diabetes 14 9.3 8 10.5 6 8.0
 Psychotic illnesse 65 43.0 37 48.7 28 37.3
 European ancestry 135 89.4 71 93.4 64 85.3

SD Standard deviation, TG Triglyceride, LDLC Low density lipoprotein cholesterol, HDLC High density lipoprotein cholesterol, TC Total cholesterol, BMI Body mass index, HTG Hypertriglyceridemia, T2D type 2 diabetes

aExcluded one individual on fibrates (n = 1)

bFor individuals on statin medications, LDLC and TC levels were divided by 0.7 and 0.8, respectively, as in previous studies [8, 9, 32]

cRecorded at the date of TC measurement to the nearest 0.1 years

dMild-moderate HTG is defined as having a TG level between 1.7–10 mmol/L. For this row only, there are n = 74 males and n = 149 total

eDefined as schizophrenia or schizoaffective disorder

Reference

  • 1.Ying S, Heung T, Thiruvahindrapuram B, et al. Polygenic risk for triglyceride levels in the presence of a high impact rare variant. BMC Med Genomics. 2023;16:281. doi: 10.1186/s12920-023-01717-2. [DOI] [PMC free article] [PubMed] [Google Scholar]

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