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Compositional changes incited by the absence of oral hygiene. Principal component analysis (PCA) was expressed using the two most decisive components (PC1 and PC2), which covered approximately 8% of the variation of the dataset. Placebo vs. probiotics day 14 (A). Placebo vs. probiotics day 28 (B). Linear discriminant analysis effect size (LEfSe) analysis expressed using significant species at day 14 (C) and day 28 (D).
