1. Randomization assignment |
1. There was clear ‘cause’ and ‘effect’ |
2. Allocation to treatment groups concealed |
2. Participants included in any comparisons were similar |
3. Treatment groups similar at the baseline |
3. Participants receiving similar treatment/care |
4. Participants blind to treatment assignment |
4. There was a control group |
5. Delivering treatment blind to treatment assignment |
5. Multiple measurements taken pre- and post-intervention |
6. Outcome assessors blind to treatment assignment |
6. Groups adequately described and analyzed |
7. Treatment groups treated identically |
7. Outcomes measured in the same way for treatment |
8. Groups adequately described and analyzed |
8. Outcomes measured in a reliable way |
9. Participants analyzed in the groups randomized |
|
10. Outcomes measured in the same way for treatment |
|
11. Outcomes measured in a reliable way |
|
12. Appropriate statistical analysis used |
|
13. Appropriate trial design |
|