Amended Figure 5 and new caption.
Figure 5.
U937 cells activated with LPS (100 ng/mL) plus TNFα (100 ng/mL) for 24 h, alone or in combination with 3 or 7 at 0.1, 1, 10, 100, and 1000 nM. Dexamethasone (Dex) was used at 5 μM. Quantitative real-time PCR analysis of expression of proinflammatory genes IL-1β (A and E), TNFα (B and F), IL-6 (C and G) and M1 marker CD11c (D and H). These data are normalized to TBP mRNA expression. Data are derived from five replicates. Results represent mean ± SEM # p < 0.05 vs NT group and *p < 0.05 vs LPS plus TNFα group. N.D. means not determined. Analysis of variance (ANOVA) was used for statistical comparisons.