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. 1984 May;41(2):260–262. doi: 10.1136/oem.41.2.260

Genotoxic exposure of workers creosoting wood.

R P Bos, C T Hulshof, J L Theuws, P T Henderson
PMCID: PMC1069342  PMID: 6722053

Abstract

In a small wood preserving industry spot samples were taken from contaminated surfaces at several places and tested for mutagenicity. The results suggest that the application of a wipe test can give a first indication of occupational exposure to mutagenic and carcinogenic substances, particularly when exposure occurs more from skin contact than from inhalation. One of the pesticide chemicals used to preserve wood is the mutagenic creosote . It was found that mutagens appeared in the urine of rats after intraperitoneal administration of creosote . Despite these results, no increase in mutagenicity could be detected in the urine of creosote workers in relation to their work.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ames B. N., Mccann J., Yamasaki E. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat Res. 1975 Dec;31(6):347–364. doi: 10.1016/0165-1161(75)90046-1. [DOI] [PubMed] [Google Scholar]
  2. Bos R. P., Brouns R. M., van Doorn R., Theuws J. L., Henderson P. T. The appearance of mutagens in urine of rats after the administration of benzidine and some other aromatic amines. Toxicology. 1980;16(2):113–122. doi: 10.1016/0300-483x(80)90042-6. [DOI] [PubMed] [Google Scholar]
  3. Bos R. P., Hulshof C. T., Theuws J. L., Henderson P. T. Mutagenicity of creosote in the Salmonella/microsome assay. Mutat Res. 1983 Jan;119(1):21–25. doi: 10.1016/0165-7992(83)90033-7. [DOI] [PubMed] [Google Scholar]
  4. van Doorn R., Bos R. P., Leijdekkers C. M., Wagenaas-Zegers M. A., Theuws J. L., Henderson P. T. Thioether concentration and mutagenicity of urine from cigarette smokers. Int Arch Occup Environ Health. 1979 Jun 15;43(3):159–166. doi: 10.1007/BF00381187. [DOI] [PubMed] [Google Scholar]

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