Abstract
How, M. J., and Cambridge, G. W. (1971).Brit. J. industr. Med.,28, 303-307. Prick-tests and serological tests in the diagnosis of allergic reactivity to enzymes used in washing products. Standardized prick-test antigens for use in the detection of allergic reactivity to enzymes (Alcalase and Maxatase) used in washing products have been prepared. These materials contained all the potentially allergenic components of the crude enzyme preparations. Tests showed that these materials were more appropriate, as prick-test antigens, than the crystalline enzyme. The presence of reagin-mediated, immediate-type allergy in factory workers was confirmed by prick-tests and passive transfer tests. Sera from these subjects and controls contained enzyme-specific haemagglutinating antibody and gave precipitin-like reactions with solutions of Alcalase and Maxatase. The latter reaction involved serum components electrophoretically similar to, or identical with, α-globulins.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ALADJEM F., MACLAREN W. R. Allergy to chymotrypsin. J Allergy. 1957 Jan;28(1):89–90. doi: 10.1016/0021-8707(57)90074-6. [DOI] [PubMed] [Google Scholar]
- BOYDEN S. V. The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. J Exp Med. 1951 Feb;93(2):107–120. doi: 10.1084/jem.93.2.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Belin L., Hoborn J., Falsen E., André J. Enzyme sensitisation in consumers of enzyme-containing washing powder. Lancet. 1970 Dec 5;2(7684):1153–1157. doi: 10.1016/s0140-6736(70)90340-5. [DOI] [PubMed] [Google Scholar]
- Eriksson S. Antitrypsin deficiency in chronic obstructive lung disease. Lancet. 1970 Apr 25;1(7652):891–892. doi: 10.1016/s0140-6736(70)91714-9. [DOI] [PubMed] [Google Scholar]
- Flindt M. L. Pulmonary disease due to inhalation of derivatives of Bacillus subtilis containing proteolytic enzyme. Lancet. 1969 Jun 14;1(7607):1177–1181. doi: 10.1016/s0140-6736(69)92165-5. [DOI] [PubMed] [Google Scholar]
- Greenberg M., Milne J. F., Watt A. Survey of workers exposed to dusts containing derivatives of Bacillus subtilis. Br Med J. 1970 Jun 13;2(5710):629–633. doi: 10.1136/bmj.2.5710.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HOWE C., ERLANGER B. F., BEISER S. M., ELLISON S. A., COHEN W. Hypersensitivity to purified trypsin and chymotrypsin. N Engl J Med. 1961 Aug 17;265:332–334. doi: 10.1056/NEJM196108172650708. [DOI] [PubMed] [Google Scholar]
- LEVY H. B., SOBER H. A. A simple chromatographic method for preparation of gamma globulin. Proc Soc Exp Biol Med. 1960 Jan;103:250–252. doi: 10.3181/00379727-103-25476. [DOI] [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- Newhouse M. L., Tagg B., Pocock S. J., McEwan A. C. An epidemiological study of workers producing enzyme washing powders. Lancet. 1970 Apr 4;1(7649):689–693. doi: 10.1016/s0140-6736(70)90924-4. [DOI] [PubMed] [Google Scholar]
- Pepys J., Longbottom J. L., Hargreave F. E., Faux J. Allergic reactions of the lungs to enzymes of Bacillus subtilis. Lancet. 1969 Jun 14;1(7607):1181–1184. doi: 10.1016/s0140-6736(69)92166-7. [DOI] [PubMed] [Google Scholar]
- Wüthrich B., Ott F. Berufsasthma durch Proteasen in der Waschmittelindustrie. Schweiz Med Wochenschr. 1969 Nov 1;99(44):1584–1586. [PubMed] [Google Scholar]