Author Correction: Integrative genetic analysis illuminates ALS heritability and identifies risk genes

Correction to: Nature Communications 10.1038/s41467-022-35724-1, published online 20 January 2023

The original version of this article contained errors in Table 2 in the variant_location, cDNA_change, protein_change and dbSNPid columns. The correct version of Table 2 is:

variant_type	variant_location	cDNA_change	protein_change	gnomAD_AF	ALS cases (n = 9390)	Control (n = 4594)	MVP	CADD	dbSNPid
missense_variant	22:g.45564104G>A	c.46G>A	p.Asp16Asn	0.000322851	11	2	0.87	26.5	rs200329756
frameshift_variant	22:g.45564091dupATAGGAATTG	c.35_45dupATAGGAATTGG	p.Asp16fs	NA	1	0	NA	NA	NA
structural	22:g.45564117A>G	c.59A>G	p.Glu20Gly	4.2e-06	3	0	0.84	26.3	rs1200142847
structural	22:g.45567544C>T	c.133C>T	p.Arg45Cys	9.68367e-05	9	0	0.89	28.1	rs113634721
missense_variant	22:g.45571835C>T	c.214C>T	p.Arg72Cys	3.23018e-05	1	0	0.81	23.6	rs781273344
splice_variant	22:g.45574119G>A	c.341G>A	p.Gly114Asp	0.000419897	3	0	0.73	24.2	rs148003438
missense_variant	22:g.45574245A>G	c.467A>G	p.Tyr156Cys	2.88367e-05	1	0	0.75	23	rs779406443
missense_variant	22:g.45574601A>G	c.823A>G	p.Lys275Glu	3.22768e-05	2	0	0.71	23.5	rs753113949
splice_acceptor	22:g.45567480G>C	c.70-1G>C	NA	3.9-06	1	0	NA	32	rs770658454
missense_variant	22:g.45574313C>G	c.535C>G	p.Pro179Ala	6.52768e-06	1	0	0.81	22.4	rs763689432
missense_variant	22:g.45580471C>T	c.1342C>T	p.Arg448Trp	6.52768e-05	1	0	0.91	24	rs777952476

which replaces the previous incorrect version:

variant_type	variant_location	cDNA_change	protein_change	gnomAD_AF	ALS cases (n = 9390)	Control (n = 4594)	MVP	CADD	dbSNPid
missense_variant	22:g.45564104G>A	c.46G>A	p.Asp16Asn	0.000322851	11	2	0.88	26.5	rs200329756
frameshift_variant	22:g.45564091dupATAGGAATTG	c.35_45dupATAGGAATTGG	p.Asp16fs	NA	1	0	NA	NA	NA
structural	22:g.45564117A>G	c.59A>G	p.Gln20Cys	4.2e-06	3	0	0.86	26.3	rs1200142847
structural	22:g.45567544C>T	c.133C>T	p.Arg45Cys	9.68367e-05	9	0	0.89	28.1	rs113634721
missense_variant	22:g.45571835C>T	c.214C>T	p.Arg72Cys	3.23018e-05	1	0	0.81	23.6	rs781273344
splice_variant	22:g.45574119G>A	c.341G>A	p.Gly114Asp	0.000419897	3	0	0.74	24.2	rs148003438
missense_variant	22:g.45574245A>G	c.467A>G	p.Tyr156Cys	2.88367e-05	1	0	0.76	23	rs779406443
missense_variant	22:g.45574601A>G	c.823A>G	p.Lys275Glu	3.22768e-05	2	0	0.71	23.5	rs753113943
splice_acceptor	22:g.45567480G>C	c.70-1G>C	NA	3.9-06	1	0	NA	32	rs770658454
missense_variant	22:g.45178432C>G	c.734C>G	p.Pro179Ala	6.52768e-06	1	0	0.81	22.4	rs763689432
missense_variant	22:g.45184590C>T	c.1734C>G	p.Arg448Trp	6.52768e-05	1	0	0.91	24	rs777952476

In addition, the original version of Fig. 3c showed one variant (Lys275Glu) in an incorrect location and another variant (Arg448Trp) was missing. The correct version of Fig. 3 is:

which replaces the previous incorrect version:

This has been corrected in both the PDF and HTML versions of the Article.