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. 2023 Nov 7;26(12):108409. doi: 10.1016/j.isci.2023.108409

Figure 2.

Figure 2

B1KO females are hyperphagic and gain more weight at the end of pregnancy body

Influence of B1R deficiency on weight gain (A) and food intake (B) during pregnancy; litter size (C), placental mass (D), litter weight (E), and placental efficiency mean per dam (F). The B1R absence increases the gestational body weight gain (genotype as the source of variation: p = 0.032) and food intake (p = 0.018), with no impact on litter size, placental weight, litter weight, and placental efficiency mean. Interaction between genotype and time was observed for gestational body weight gain (p = 0.036). ∗p < 0.05, ∗∗p < 0.01. Data were compared by two-way ANOVA with Sidak’s multiple comparison test (A), Mann-Whitney (C), and Student’s unpaired t test (B, D, E, and F) at GraphPad Prism 7. Values expressed as mean ± SD of 8–11 mice per group. AUC – area under the curve. Blue = WT dam; Red = B1KO dam. See also Figure S2.