Table 3.
Median [P25–P75] protein intake (TP, PS and NP) according to age, PKU severity and type of treatment.
| TP Intake (g/kg) Median [P25–P75] |
PS Intake (g/kg) Median [P25–P75] |
NP Intake (g/kg) Median [P25–P75] |
||
|---|---|---|---|---|
| Age | <12 years (n = 18) | 1.68 [1.42–2.03] | 0.9 [0.05–1.06] | 0.6 [0.49–1.65] |
| ≥12 years (n = 81) | 1.42 [1.17–1.71] | 0.67 [0–0.87] | 0.73 [0.39–1.4] | |
| PKU severity | HPA (n = 24) | 1.8 [1.42–2.08] | 0 [0–0] | 1.8 [1.42–2.08] |
| Mild (n = 48) | 1.53 [1.29–1.73] | 0.78 [0.26–1.02] | 0.68 [0.48–1.15] | |
| Classical (n = 27) | 1.28 [1.12–1.41] | 0.87 [0.72–0.98] | 0.34 [0.25–0.49] | |
| Type of treatment | Diet only (n = 82) | 1.43 [1.24–1.79] | 0.72 [0–0.98] | 0.6 [0.35–1.45] |
| Diet + BH4 therapy (n = 17) |
1.57 [1.29–1.71] | 0.5 [0.25–0.78] | 1 [0.79–1.2] |
Abbreviations: PKU—phenylketonuria; HPA—hyperphenylalaninemia; BH4—tetrahydrobiopterin; TP—total protein; PS—protein substitutes and NP—natural protein.