Corrigendum to: Impact of extent of resection on outcome from glioblastoma using the RANO resect group classification system: a retrospective, population-based cohort study

This is a corrigendum to: Line Sagerup Bjorland, Rupavathana Mahesparan, Øystein Fluge, Bjørnar Gilje, Kathinka Dæhli Kurz, Elisabeth Farbu, Impact of extent of resection on outcome from glioblastoma using the RANO resect group classification system: a retrospective, population-based cohort study, Neuro-Oncology Advances, Volume 5, Issue 1, January-December 2023, vdad126, https://doi.org/10.1093/noajnl/vdad126

In the originally published version of this manuscript, there was an error in the univariate analysis presented in Table 3. The Hazard Ratios of the effect of extent of resection were based on opposite reference level of extent of resection. The correct reference level is complete CE resection (EOR class 2A). This has been corrected online.

Table 3.

Unadjusted and Adjusted Cox Proportional Hazard Ratio on Survival in 235 Patients in Western Norway With Histologically Confirmed Glioblastoma Between 1.1.2007 and 31.12.2014

	Univariable analysis			Multivariable analysis
	HR	95% CI	P value	HR	95% CI	P value
Sex (female)	0.91	0.70–1.18	0.47	1.07	0.81–1.41	0.65
Age (per year)	1.03	1.02–1.04	<0.001	1.03	1.02–1.04	<0.001
Deep-seated tumor*	1.53	0.92–2.55	0.10	1.37	0.79–2.39	0.27
Multifocality	1.77	1.30–2.42	<0.001	1.54	1.11–2.14	0.01
RT/TMZ (Stupp† vs all other)	0.44	0.34–0.58	<0.001	0.60	0.44–0.82	0.001
EOR (RANO resect group classification)‡
Class 2A	Ref		Ref	Ref		Ref
Class 2B	1.93	1.30–2.86	0.001	2.33	1.56–3.47	<0.001
Class 3A	2.12	1.43–3.14	<0.001	2.00	1.35–2.96	0.001
Class 3B	2.91	1.86–4.55	<0.001	2.40	1.52–3.77	<0.001
Class 4 (biopsy)	2.52	1.75–3.61	<0.001	1.99	1.33–2.98	0.001

Abbreviations: HR = hazard ratio; CI = confidence interval; RT/TMZ = radiotherapy/temozolomide; EOR = extent of resection; RANO = response assessment in neuro-oncology; CE = contrast enhancement.

Extent of resection classified according to RANO resect group classification system (Karschnia et al., 2022). P values <0.05 considered statistical significant and marked in bold.

*Deep-seated defined as tumor located mainly in deep structures including thalamus, basal ganglia, internal capsule, splenium corpus callosum, mesencephalon, brain stem and cerebellar vermis.

^†Here defined as RT 60 Gy in 2 Gy fraction and completed at least one out six planned TMZ courses.

^‡EOR class2A = complete CE resection; class 2B = near total CE resection/<1 cm³ residual volume; class 3A = subtotal CE resection/≤5 cm³ CE; class 3B = partial CE resection/>5 cm³CE; class 4 = biopsy/no reduction of tumor volume.