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. 2023 Dec 13;108(1):45–71. doi: 10.1097/TP.0000000000004624

TABLE 1.

Commonly used PBT setsa

Transcript set Abbreviation Description of the transcripts
TCMR-related QCAT Cytotoxic T cell associated43
AMR-related DSAST DSA selective44
NKB NK cell transcript burden45
AMR-RATb AMR selective46
GRIT Interferon gamma-inducible47
Increased after recent injury IRRAT30 Injury-repair response associated48
FICOL Fibrillar collagen transcripts49
IRITD3 Injury-repair induced transcripts, day 350
IRITD5 Injury-repair induced transcripts, day 550
Atrophy-fibrosis IGT Immunoglobulin transcripts51
b

The abbreviation AMR is used by journal convention but official abbreviations used in the MMDx papers and website is usually “ABMR.”

AMR, antibody-mediated rejection; DSA, donor-specific antibody; DSAT, DSA-selective transcripts; FICOL, fibrillar collagen; GRIT, IFNG-inducible transcripts; IGT, immunoglobulin transcripts; IRITD3, injury-repair induced, day 3; IRITD5, injury-repair induced, day 5; IRRAT, injury- and rejection-associated transcript; NKB, NK cell burden; PBT, pathogenesis-based transcript; QCAT, cytotoxic CD8 T cell-associated transcript; TCMR, T cell–mediated rejection.