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[Preprint]. 2023 Dec 10:2023.12.09.570874. [Version 1] doi: 10.1101/2023.12.09.570874

Figure 3. Variants at SIRPA are associated with platelet levels.

Figure 3.

(A) Variation at 3’ to CD47 at BBX locus associated with platelet levels. (B) Variant rs3197744 at SIRPA locus associates with amount of platelets. (C) Examining associations across currently available GWAS results (PheWAS) over 2500 independent studies at rs3197744 at SIRPA locus shows specific association with platelet and immune cell measurements. (D) Expression profile of SIRPA across human tissues shows highest expression in the brain and in blood.