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. 1955 Jun;34(6):808–819. doi: 10.1172/JCI103136

Simultaneous Estimation of Rates of Thyroxine Degradation and Thyroid Hormone Synthesis1

Sidney H Ingbar a,2, Norbert Freinkel a,3
PMCID: PMC1072611  PMID: 14381510

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALBERT A., KEATING F. R., Jr Metabolic studies with I131 labeled thyroid compounds; comparison of the distribution and fate of radioactive d-1-thyroxine after oral and intravenous administration in the human. J Clin Endocrinol Metab. 1949 Dec;9(12):1406–1421. doi: 10.1210/jcem-9-12-1406. [DOI] [PubMed] [Google Scholar]
  2. ALBERT A., KEATING F. R., Jr The role of the gastrointestinal tract, including the liver, in the metabolism of radiothyroxine. Endocrinology. 1952 Nov;51(5):427–443. doi: 10.1210/endo-51-5-427. [DOI] [PubMed] [Google Scholar]
  3. BARKER S. B., HUMPHREY M. J., SOLEY M. H. The clinical determination of protein-bound iodine. J Clin Invest. 1951 Jan;30(1):55–62. doi: 10.1172/JCI102416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BENUA R. S., ALBERT A., KEATING F. R., Jr The metabolism of radiothyroxine in exophthalmic goiter. J Clin Endocrinol Metab. 1952 Nov;12(11):1461–1473. doi: 10.1210/jcem-12-11-1461. [DOI] [PubMed] [Google Scholar]
  5. BERSON S. A., YALOW R. S. Quantitative aspects of iodine metabolism: the exchangeable organic iodine pool, and the rates of thyroidal secretion, peripheral degradation and fecal excretion, of endogenously synthesized organically bound iodine. J Clin Invest. 1954 Nov;33(11):1533–1552. doi: 10.1172/JCI103032. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. BERSON S. A., YALOW R. S., SCHREIBER S. S., POST J. Tracer experiments with I131 labeled human serum albumin: distribution and degradation studies. J Clin Invest. 1953 Aug;32(8):746–768. doi: 10.1172/JCI102789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. DEISS W. P., ALBRIGHT E. C., LARSON F. C. A study of the nature of the circulating thyroid hormone in euthyroid and hyperthyroid subjects by use of paper electrophoresis. J Clin Invest. 1952 Nov;31(11):1000–1005. doi: 10.1172/JCI102683. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. FAWCETT D. M., KIRKWOOD S. Tyrosine iodinase. J Biol Chem. 1954 Jul;209(1):249–256. [PubMed] [Google Scholar]
  9. GROSS J., LEBLOND C. P. Metabolism of the thyroid hormone in the rat as shown by physiological doses of labeled thyroxine. J Biol Chem. 1950 Jun;184(2):489–500. [PubMed] [Google Scholar]
  10. HAMOLSKY M. W., FREEDBERG A. S., KURLAND G. S., WOLSKY L. The exchangeable thyroid hormonal pool. I. Its magnitude and rate of turnover in various thyroid states in man. J Clin Invest. 1953 May;32(5):453–457. doi: 10.1172/JCI102759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. INGBAR S. H., FREINKEL N., HOEPRICH P. D., ATHENS J. W. The concentration and significance of the butanol-extractable I131 of serum in patients with diverse states of thyroidal function. J Clin Invest. 1954 Mar;33(3):388–399. doi: 10.1172/JCI102911. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. INGBAR S. H. Simultaneous measurement of the iodide-concentrating and protein-binding capacities of the normal and hyperfunctioning human thyroid gland. J Clin Endocrinol Metab. 1955 Feb;15(2):238–264. doi: 10.1210/jcem-15-2-238. [DOI] [PubMed] [Google Scholar]
  13. Palmer W. W., Leland J. P. COMPARATIVE CALORIGENIC ACTION OF NORMAL AND PATHO-LOGICAL THYROID GLANDS ADMINISTERED IN EQUI-THYROXINE DOSES. J Clin Invest. 1935 Sep;14(5):619–631. doi: 10.1172/JCI100711. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. RIGGS D. S. Quantitative aspects of iodine metabolism in man. Pharmacol Rev. 1952 Sep;4(3):284–370. [PubMed] [Google Scholar]
  15. ROSENMAN R. H., BYERS S. O., FRIEDMAN M. The mechanism responsible for the altered blood cholesterol content in deranged thyroid states. J Clin Endocrinol Metab. 1952 Oct;12(10):1287–1299. doi: 10.1210/jcem-12-10-1287. [DOI] [PubMed] [Google Scholar]
  16. STANBURY J. B., BROWNELL G. L., RIGGS D. S., PERINETTI H., DEL CASTILLO E., ITOIZ J., HOUSSAY A., TRUCCO E., YACIOFANO A. C. The iodine-deficient human thyroid gland; a preliminary report. J Clin Endocrinol Metab. 1952 Feb;12(2):191–207. doi: 10.1210/jcem-12-2-191. [DOI] [PubMed] [Google Scholar]
  17. THODE H. G., JAIMET C. H., KIRKWOOD S. Studies and diagnostic tests of salivary-gland and thyroid-gland function with radioiodine. N Engl J Med. 1954 Jul 22;251(4):129–134. doi: 10.1056/NEJM195407222510402. [DOI] [PubMed] [Google Scholar]

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