Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1957 Aug;36(8):1217–1226. doi: 10.1172/JCI103518

The Distribution and Excretion of Phenobarbital1

William J Waddell a,2, Thomas C Butler a
PMCID: PMC1072713  PMID: 13463084

Full text

PDF
1217

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BATTERMAN R. C., SOMMER E. M. Fate of gentisic acid in man as influenced by alkalinization and acidification. Proc Soc Exp Biol Med. 1953 Mar;82(3):376–379. doi: 10.3181/00379727-82-20121. [DOI] [PubMed] [Google Scholar]
  2. BERLINER R. W. The kidney. Annu Rev Physiol. 1954;16:269–304. doi: 10.1146/annurev.ph.16.030154.001413. [DOI] [PubMed] [Google Scholar]
  3. BRODIE B. B., MARK L. C. The fate of thiopental in man and a method for its estimation in biological material. J Pharmacol Exp Ther. 1950 Jan;98(1):85–96. [PubMed] [Google Scholar]
  4. BRODWALL E., STOA K. F. A study of barbiturate clearance. Acta Med Scand. 1956 Mar 26;154(2):139–144. doi: 10.1111/j.0954-6820.1956.tb14307.x. [DOI] [PubMed] [Google Scholar]
  5. BUTLER T. C., MAHAFFEE C., WADDELL W. J. Phenobarbital: studies of elimination, accumulation, tolerance, and dosage schedules. J Pharmacol Exp Ther. 1954 Aug;111(4):425–435. [PubMed] [Google Scholar]
  6. BUTLER T. C. The effects of N-methylation in 5,5-disubstituted derivatives of barbituric acid, hydantoin, and 2-4-oxazolidinedione. J Am Pharm Assoc Am Pharm Assoc. 1955 Jun;44(6):367–370. doi: 10.1002/jps.3030440618. [DOI] [PubMed] [Google Scholar]
  7. BUTLER T. C. The metabolic hydroxylation of phenobarbital. J Pharmacol Exp Ther. 1956 Mar;116(3):326–336. [PubMed] [Google Scholar]
  8. CRAIG W. S., KITCHING G. A., DAVIES I. G., BROCKINGTON C. F. Continuing nursing care for the small infant discharged from hospital. Br Med J. 1951 Jun 2;1(4717):1234–1236. doi: 10.1136/bmj.1.4717.1234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. DALGAARD-MIKKELSEN S. On the renal excretion of salicylate. Acta Pharmacol Toxicol (Copenh) 1951;7(3):243–258. doi: 10.1111/j.1600-0773.1951.tb02867.x. [DOI] [PubMed] [Google Scholar]
  10. GIOTTI A., MAYNERT E. W. The renal clearance of barbital and the mechanism of its reabsorption. J Pharmacol Exp Ther. 1951 Mar;101(3):296–309. [PubMed] [Google Scholar]
  11. GOLDBAUM L. R., SMITH P. K. The interaction of barbiturates with serum albumin and its possible relation to their disposition and pharmacological actions. J Pharmacol Exp Ther. 1954 Jun;111(2):197–209. [PubMed] [Google Scholar]
  12. GUTMAN A., YU T. F., SIROTA J. H. A study, by simultaneous clearance techniques, of salicylate excretion in man: effect of alkalinization of the urine by bicarbonate administration; effect of probenecid. J Clin Invest. 1955 May;34(5):711–721. doi: 10.1172/JCI103124. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. LOUS P. Barbituric acid concentration in serum from patients with severe acute poisoning. Acta Pharmacol Toxicol (Copenh) 1954;10(3):261–280. doi: 10.1111/j.1600-0773.1954.tb01343.x. [DOI] [PubMed] [Google Scholar]
  14. LOUS P. Blood serum and cerebrospinal fluid levels and renal clearance of phenemal in treated epileptics. Acta Pharmacol Toxicol (Copenh) 1954;10(2):166–177. doi: 10.1111/j.1600-0773.1954.tb01333.x. [DOI] [PubMed] [Google Scholar]
  15. LOUS P. Plasma levels and urinary excretion of three barbituric acids after oral administration to man. Acta Pharmacol Toxicol (Copenh) 1954;10(2):147–165. doi: 10.1111/j.1600-0773.1954.tb01332.x. [DOI] [PubMed] [Google Scholar]
  16. MACPHERSON C. R., MILNE M. D., EVANS B. M. The excretion of salicylate. Br J Pharmacol Chemother. 1955 Dec;10(4):484–489. doi: 10.1111/j.1476-5381.1955.tb00109.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. OHLSSON W. T. L. Blodsköljningsbehandling vid svår akut barbiturförgiftning. Nord Med. 1949 Sep 9;42(36):1471–1473. [PubMed] [Google Scholar]
  18. ORLOFF J., BERLINER R. W. The mechanism of the excretion of ammonia in the dog. J Clin Invest. 1956 Feb;35(2):223–235. doi: 10.1172/JCI103267. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Reiner M., Fenichel R. L. Dialysis of Protein Solutions for Electrophoresis. Science. 1948 Aug 13;108(2798):164–166. doi: 10.1126/science.108.2798.164. [DOI] [PubMed] [Google Scholar]
  20. WRIGHT J. T., JOHNS R. G. S. A study of barbiturate intoxication by an ultra-violet spectrophotometric technique. J Clin Pathol. 1953 Feb;6(1):78–83. doi: 10.1136/jcp.6.1.78. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. WRIGHT J. T. The value of barbiturate estimations in the diagnosis and treatment of barbiturate intoxication. Q J Med. 1955 Jan;24(93):95–108. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES