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. 1957 Sep;36(9):1313–1318. doi: 10.1172/JCI103529

Thyroid-Adrenocortical Interrelations: Failure to Demonstrate Antagonism Between Triiodo-thyronine and Hydrocortisone in Man1

Kenneth Fremont-Smith a,2, Frank L Iber a,3, Irvin C Plough a,4
PMCID: PMC1072728  PMID: 13463095

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERSON S. A., YALOW R. S. The effect of cortisone on the iodine accumulating function of the thyroid gland in euthyroid subjects. J Clin Endocrinol Metab. 1952 Apr;12(4):407–422. doi: 10.1210/jcem-12-4-407. [DOI] [PubMed] [Google Scholar]
  2. ENGSTROM W. W., MARKARDT B. The effects of serious illness and surgical stress on the circulating thyroid hormone. J Clin Endocrinol Metab. 1955 Aug;15(8):953–963. doi: 10.1210/jcem-15-8-953. [DOI] [PubMed] [Google Scholar]
  3. FORSYTH B. T., SHIPMAN M. E., PLOUGH I. C. The variability of fecal nitrogen excretion with liquid and solid diets. J Lab Clin Med. 1954 Mar;43(3):440–444. [PubMed] [Google Scholar]
  4. FREDRICKSON D. S., FORSHAM P. H., THORN G. W. The effect of massive cortisone therapy on measurements of thyroid function. J Clin Endocrinol Metab. 1952 May;12(5):541–553. doi: 10.1210/jcem-12-5-541. [DOI] [PubMed] [Google Scholar]
  5. GOLDENBERG I. S., LUTWAK L., ROSENBAUM P. J., HAYES M. A. Thyroid activity during operation. Surg Gynecol Obstet. 1956 Feb;102(2):129–133. [PubMed] [Google Scholar]
  6. GOLDENBERG I. S., LUTWAK L., ROSENBAUM P. J., HAYES M. A. Thyroid-adrenocortical metabolic interrelations. J Clin Endocrinol Metab. 1955 Feb;15(2):227–237. doi: 10.1210/jcem-15-2-227. [DOI] [PubMed] [Google Scholar]
  7. GOLDENBERG I. S., LUTWAK L., ROSENBAUM P. J., HAYES M. A. Thyroidadrenocortical interrelations following operation. Surg Gynecol Obstet. 1954 May;98(5):513–522. [PubMed] [Google Scholar]
  8. GROSS J., PITT-RIVERS R. Physiological activity of 3:5:3'-L-triiodothyronine. Lancet. 1952 Mar 22;1(6708):593–594. doi: 10.1016/s0140-6736(52)90104-9. [DOI] [PubMed] [Google Scholar]
  9. HILL S. R., Jr, REISS R. S., FORSHAM P. H., THORN G. W. The effect of adrenocorticotropin and cortisone on thyroid function; thyroid-adrenocortical interrelationships. J Clin Endocrinol Metab. 1950 Nov;10(11):1375–1400. doi: 10.1210/jcem-10-11-1375. [DOI] [PubMed] [Google Scholar]
  10. INGBAR S. H. The effect of cortisone on the thyroidal and renal metabolism of iodine. Endocrinology. 1953 Aug;53(2):171–181. doi: 10.1210/endo-53-2-171. [DOI] [PubMed] [Google Scholar]
  11. MOORE F. D., STEENBURG R. W., BALL M. R., WILSON G. M., MYRDEN J. A. Studies in surgical endocrinology. I. The urinary excretion of 17-hydroxycorticoids, and associated metabolic changes, in cases of soft tissue trauma of varying severity and in bone trauma. Ann Surg. 1955 Feb;141(2):145–174. doi: 10.1097/00000658-195502000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. PARIS J., FORD E., LORENZ N., KEATING F. R., Jr, ALBERT A. Effect of hormones on renal clearance of radioiodine in the rat. Am J Physiol. 1955 Oct;183(1):163–166. doi: 10.1152/ajplegacy.1955.183.1.163. [DOI] [PubMed] [Google Scholar]
  13. PERRY W. F., GEMMELL J. P. The effect of surgical operations on the excretion of iodine, corticosteroids, and uric acid. Can J Res. 1949 Dec;27(6 SECT):320–326. doi: 10.1139/cjr49e-042. [DOI] [PubMed] [Google Scholar]
  14. PETERSON R. E., WYNGAARDEN J. B., GUERRA S. L., BRODIE B. B., BUNIM J. J. The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest. 1955 Dec;34(12):1779–1794. doi: 10.1172/JCI103233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PORTER C. C., SILBER R. H. A quantitative color reaction for cortisone and related 17,21-dihydroxy-20-ketosteroids. J Biol Chem. 1950 Jul;185(1):201–207. [PubMed] [Google Scholar]
  16. ROMANOFF E. B., HUDSON P., PINCUS G. Isolation of hydrocortisone and corticosterone from human adrenal vein blood. J Clin Endocrinol Metab. 1953 Dec;13(12):1546–1548. doi: 10.1210/jcem-13-12-1546. [DOI] [PubMed] [Google Scholar]
  17. SANDBERG A. A., EIK-NES K., SAMUELS L. T., TYLER F. H. The effects of surgery on the blood levels and metabolism of 17-hydroxycorticosteroids in man. J Clin Invest. 1954 Nov;33(11):1509–1516. doi: 10.1172/JCI103029. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. SAYERS G. The adrenal cortex and homoestasis. Physiol Rev. 1950 Jul;30(3):241–320. doi: 10.1152/physrev.1950.30.3.241. [DOI] [PubMed] [Google Scholar]
  19. SHIPLEY R. A., MACINTYRE F. H. Effect of stress, TSH and ACTH on the level of hormonal I131 of serum. J Clin Endocrinol Metab. 1954 Mar;14(3):309–317. doi: 10.1210/jcem-14-3-309. [DOI] [PubMed] [Google Scholar]
  20. SHIPLEY R. A., MACINTYRE F. H. Effect of stress, TSH and ACTH on the level of hormonal I131 of serum. J Clin Endocrinol Metab. 1954 Mar;14(3):309–317. doi: 10.1210/jcem-14-3-309. [DOI] [PubMed] [Google Scholar]
  21. TAPLEY D. F. Magnesium balance in myxedematous patients treated with triiodothyronine: preliminary note. Bull Johns Hopkins Hosp. 1955 Jun;96(6):274–278. [PubMed] [Google Scholar]
  22. WOLFSON W. Q., BEIERWALTES W. H., ROBINSON W. D., DUFF I. F., JONES J. R., KNORPP C. T., EYA M. Corticogenic hypothyroidism; its regular occurrence and clinical significance during prolonged therapeutic administration of ACTH or cortisone. J Lab Clin Med. 1950 Dec;36(6):1005–1006. [PubMed] [Google Scholar]

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